# 4,4'-Oxydianiline

URL: https://app.greenveil.ai/ingredients/ingredient_cas_101_80_4
Categories: beauty, industrial
Functions: Chemical reaction regulator, crosslinking / coupling / curing agents > amines, diamines, Hardener
Identifier: 101-80-4

> 4,4'-Oxydianiline is used as chemical reaction regulator / crosslinking / coupling / curing agents > amines. Greenveil chemical-concern score: 100/100 — Critical concern driven by cmr.. Assessed from 6 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern driven by cmr.
- Confidence: 4
- Rationale: 4,4'-Oxydianiline (p-aminophenyl ether) and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1B(),Mutagenic Cat. 1B(),Reprotoxic Cat. 2()
- US: commercial use observed — EPA CPDat observed this chemical in 2 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Chemical reaction regulator, Hardener, diamines.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._