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  1. Ingredients
  2. beauty
  3. Bisoctrizole
  • beauty
  • industrial
  • pharma

Bisoctrizole

CAS 103597-45-1 · 25/100 · High conf.

Uv filter · Stabilizing agent · UV stabilizer

Bisoctrizole chemical structure
25

Concern score

25/100Minor concern based on regulatory listings.
Well researched
Bisoctrizole chemical structure

Why it's flagged

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano) is listed in Annex VI of the EU Cosmetics Regulation (EC) 1223/2009 (UV filters allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Bisoctrizole appears in these published regulatory listings.

  • commercial_presence
  • cpdat_category:industrial
  • currently_marketed_ndc
  • definition_level:complete
  • definition_type:primary
  • eu_annex:VI
  • eu_cosmetic_allowed_uv_filter
  • ingredient_type:ingredient substance
  • EUECallowed_listed2 entries
    • Annex VI of EU Cosmetics Regulation (EC) 1223/2009: UV filters allowed in cosmetic products. Maximum concentration: 10 %(*) (*) In case of combined use of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol and Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano), the sum shall not exceed the limit given in column g.’. Other conditions: Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — Purity ≥ 98,5 %, with 2,2′-methylene-bis- (6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) isomer fraction not exceeding 1,5 %; — Solubility < 5 ng/L in water at 25 °C; — Partition coefficient (Log Pow): 12,7 at 25 °C; —…Source →
    • Annex VI of EU Cosmetics Regulation (EC) 1223/2009: UV filters allowed in cosmetic products. Maximum concentration: 10%Source →
  • USFDAmarketed drug occurrence2 entries
    • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
    • FDA NDC lists this ingredient in 5 active drug products and 5 total products.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including UV stabilizer, Stabilizing agent.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including UV stabilizer, Stabilizing agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Evidence

No graded sources yet for Bisoctrizole. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it appears

Prevalence of Bisoctrizole in our catalog (fda_ndc).

Products

1

Typical roles

Uv filterStabilizing agentUV stabilizer
See products using Bisoctrizole →

Catalog

Found in these products

18 products
  • KKalos K
    KalosKalos · DairiesMinor
  • GGreenveil G
    centella sun creamNon Food ProductsLow
  • AAvène A
    Très Haute protection 50+ latte bambinoAvèneLow
  • AAvène A
    Mat perfect FPS 50+ Fluido con colorAvène · SuncareMinor
  • AAvène A
    Eau thermale SPF 20Avène · SuncareCritical
  • GGreenveil G
    piz buinCritical
  • GGreenveil G
    Portia MNon Food ProductsCritical
  • GGreenveil G
    piz buin 30Minor
  • GGreenveil G
    Biodermal Hydraplus SPF50+ ZonnesprayVerzorgingMinor
  • EEclipsol E
    Ultra cremaEclipsol · Non Food ProductsLow
  • NNoreva N
    Exfoliac SPF 50+NorevaLow
  • CCalypso C
    facial protectionCalypso · FaceLow
  • DFDoctor Fiterman DF
    Sun ProtectDoctor Fiterman · SuncareLow
  • CPCosmica, Perrigo CP
    Sun SprayCosmica, Perrigo · SuncareLow
  • GGreenveil G
    simonds pantalla solar cremaHigh
  • Ssasi S
    AcneSol SPF50+ comfort sunscreensasi · SuncareCritical
  • SPSUN Pharma SP
    Photostable GoldSUN Pharma · SuncareHigh
  • DADot and key DA
    Dot and key Watermelon cooling sunscreenDot and key · SuncareMinor