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Methylene bis-benzotriazolyl tetramethylbutylphenol

CAS 103597-45-1 · 20/100 · High conf.

Also registered as 8 other CAS numbers

126269-45-2 · 165670-11-1 · 184484-30-8 · 192209-76-0 · 215809-89-5 · 737758-68-8 · 1202656-45-8 · 2192337-11-2

Methylene bis-benzotriazolyl tetramethylbutylphenol chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Methylene bis-benzotriazolyl tetramethylbutylphenol in plain language

What it is

On cosmetic ingredient lists it appears as “Methylene bis-benzotriazolyl tetramethylbutylphenol (nano)”.

Also known as Methylene bis-benzotriazolyl tetramethylbutylphenol (nano) · Bisoctrizole · 2,2′-Methylenebis · 2,2'-Methylenebis · 2,2'-methylene bis(4-1,1,3,3-tetra methyl butyl)-6- · 2,2'Methylenbis

Show all 13 names

Methylene bis · Bisoctrizol · Fat 75'634 · FAT-75634 · From the skin Glutathione Collagen Sun Gel Patch · Mbbt · bisoctrizolum

What it does

Used in cosmetics as a UV filter and a light stabiliser. Methylene Bis-Benzotriazolyl Tetramethylbutylphenol is the heterocyclic compound.

  • UV filter
  • Light stabilizer
  • Stabiliser
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — Methylene bis-benzotriazolyl tetramethylbutylphenol appears on published "allowed" regulatory lists rather than on a restriction list.

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano) is listed in Annex VI of the EU Cosmetics Regulation (EC) 1223/2009 (UV filters allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Methylene bis-benzotriazolyl tetramethylbutylphenol appears in these published regulatory listings.

  • In marketed US drugs
  • EU Annex VI — permitted UV filter
  • EU permitted UV filter

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActive3 entries
    • Cosmetics Regulation annex VI / ref 23.Source →
    • Methylene Bis-Benzotriazolyl Tetramethylbutylphenol is the heterocyclic compound that conforms to the formula: Restriction: VI/23Source →
    • Cosmetics Regulation annex VI / ref 23a.Source →
  • EUECallowed_listed2 entries
    • Annex VI of EU Cosmetics Regulation (EC) 1223/2009: UV filters allowed in cosmetic products. Maximum concentration: 10 %(*) (*) In case of combined use of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol and Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano), the sum shall not exceed the limit given in column g.’. Other conditions: Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — Purity ≥ 98,5 %, with 2,2′-methylene-bis- (6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) isomer fraction not exceeding 1,5 %; — Solubility < 5 ng/L in water at 25 °C; — Partition coefficient (Log Pow): 12,7 at 25 °C; —…Source →
    • Annex VI of EU Cosmetics Regulation (EC) 1223/2009: UV filters allowed in cosmetic products. Maximum concentration: 10%Source →
  • USFDAmarketed drug occurrence2 entries
    • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
    • FDA NDC lists this ingredient in 5 active drug products and 5 total products.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including UV stabilizer, Stabilizing agent.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including UV stabilizer, Stabilizing agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Methylene bis-benzotriazolyl tetramethylbutylphenol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Methylene bis-benzotriazolyl tetramethylbutylphenol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2020-07-27

    Open →

  • EPA Chemical and Products Database

    exposure · updated 23/01/2020

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2026-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Methylene bis-benzotriazolyl tetramethylbutylphenol in a product composition. These are source records, not Greenveil catalog products.

Source records

1

Typical roles

UV filterLight stabilizerStabiliser
See products using Methylene bis-benzotriazolyl tetramethylbutylphenol →

Catalog

Found in these products

Their ingredient lists include Methylene bis-benzotriazolyl tetramethylbutylphenol; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 67 →Find products without it →