# Bisoctrizole

URL: https://app.greenveil.ai/ingredients/ingredient_cas_103597_45_1
Categories: beauty, industrial, pharma
Functions: uv filter, Stabilizing agent, UV stabilizer
Identifier: 103597-45-1

> Bisoctrizole is used as uv filter / stabilizing agent. Greenveil chemical-concern score: 25/100 — Minor concern based on regulatory listings.. Assessed from 9 sources.

## Safety assessment

- Chemical concern score: 25/100 — Minor concern based on regulatory listings.
- Confidence: 4
- Rationale: Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano) is listed in Annex VI of the EU Cosmetics Regulation (EC) 1223/2009 (UV filters allowed in cosmetic products).

## Regulatory status

- EU: allowed_listed — Annex VI of EU Cosmetics Regulation (EC) 1223/2009: UV filters allowed in cosmetic products. Maximum concentration: 10 %(*) (*) In case of combined use of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol and Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano), the sum shall not exceed the limit given in column g.’. Other conditions: Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — Purity ≥ 98,5 %, with 2,2′-methylene-bis- (6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) isomer fraction not exceeding 1,5 %; — Solubility < 5 ng/L in water at 25 °C; — Partition coefficient (Log Pow): 12,7 at 25 °C; —…
- EU: allowed_listed — Annex VI of EU Cosmetics Regulation (EC) 1223/2009: UV filters allowed in cosmetic products. Maximum concentration: 10%
- US: commercial use observed — EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including UV stabilizer, Stabilizing agent.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 1 active drug products and 1 total products.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 5 active drug products and 5 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._