Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
CAS 108-10-1 · 100/100 · High conf.
1338234-91-5
Concern score
Also known as Methyl isobutyl ketone · 4-METHYL-2-PENTANONE · Isopropylacetone · Methylisobutylketone · 4-methylpentan-2-one; isobutyl methyl ketone (MIBK) · 4-Methylpentan-2-one
2-Methyl-4-pentanone · 2-Methylpropyl methyl ketone · 2-Pentanone, 4-methyl- · 4-METHYL-2-PENTANON · 4-Methyl-2-oxopentane · 4-methyl-2-pentanone, hexanone · Hexon · Hexone · Isobutyl methyl ketone · Isobutyl-methylketon · Isohexanone · Isopropyl acetone · Methyl-isobutyl-cetone · Methylisobutylketon · Metilisobutilchetone · Metyloizobutyloketon · Shell mibk · methyl isobutyl ketone (sara 313) (cercla)(vp = 15 @ 68f) · methyl isobutyl ketone (sara iii) · methyl isobutyl ketone (sara 313) (vp: 15 mmgh @ 68f) · n-butyl acetate (vp = 13 @ 68f)
Used in cosmetics as a solvent, a fragrance ingredient and a denaturant.
4-methylpentan-2-one; isobutyl methyl ketone (MIBK) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Restrictions first, then routine listings from published regulatory sources.
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()
No expert opinion on file for Mibk. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
No graded research studies for Mibk yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
CosIng
regulatory · updated 2026-09-23
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2022-11-11
EPA Chemical and Products Database
exposure · updated october 24, 2019
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
FDA GSRS UNII
registry · updated 2026-02-26
openFDA Substance
registry · updated 2026-05-24
PubChem Live Enrichment
chemistry · updated 2026-05-17
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
How often EPA CPDat has listed Mibk in a product composition. These are source records, not Greenveil catalog products.
Source records
4,754
Named organisations
6
Typical roles