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Mibk

CAS 108-10-1 · 100/100 · High conf.

Also registered as 1 other CAS number

1338234-91-5

Mibk chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

Mibk in plain language

What it is

Also known as Methyl isobutyl ketone · 4-METHYL-2-PENTANONE · Isopropylacetone · Methylisobutylketone · 4-methylpentan-2-one; isobutyl methyl ketone (MIBK) · 4-Methylpentan-2-one

Show all 27 names

2-Methyl-4-pentanone · 2-Methylpropyl methyl ketone · 2-Pentanone, 4-methyl- · 4-METHYL-2-PENTANON · 4-Methyl-2-oxopentane · 4-methyl-2-pentanone, hexanone · Hexon · Hexone · Isobutyl methyl ketone · Isobutyl-methylketon · Isohexanone · Isopropyl acetone · Methyl-isobutyl-cetone · Methylisobutylketon · Metilisobutilchetone · Metyloizobutyloketon · Shell mibk · methyl isobutyl ketone (sara 313) (cercla)(vp = 15 @ 68f) · methyl isobutyl ketone (sara iii) · methyl isobutyl ketone (sara 313) (vp: 15 mmgh @ 68f) · n-butyl acetate (vp = 13 @ 68f)

What it does

Used in cosmetics as a solvent, a fragrance ingredient and a denaturant.

  • Solvent
  • Perfuming
  • Denaturant
  • Fragrance
  • Flavouring
Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

4-methylpentan-2-one; isobutyl methyl ketone (MIBK) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()

    banned
    View source →
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex II / ref 1689.Source →
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 4754 composition records across product categories including Furniture and furnishings, Raw materials, Home maintenance. EPA CPDat classifies this chemical for functional uses including Solvent, Fragrance, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 4754 composition records across product categories including Furniture and furnishings, Raw materials, Home maintenance. EPA CPDat classifies this chemical for functional uses including Solvent, Fragrance, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Mibk. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Mibk yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2022-11-11

    Open →
  • EPA Chemical and Products Database

    exposure · updated october 24, 2019

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Mibk in a product composition. These are source records, not Greenveil catalog products.

Source records

4,754

Named organisations

6

Furniture and furnishingsRaw materialsHome maintenanceCleaning and safetyConstructionUnknown or Indeterminate

Typical roles

SolventPerfumingDenaturantFragranceFlavouring
See products using Mibk →