- beauty
- cleaning
- industrial
- pharma
Toluene
CAS 25013-04-1 · 70/100 · High conf.
Also registered as 3 other CAS numbers
1053657-77-4 · 1202864-97-8 · 108-88-3
Concern score
Toluene in plain language
Also known as Antisal 1A · Methacide · 1-Methylbenzene · Benzene, methyl- · Caswell No. 859 · Methyl benzene
Show all 26 names
Methane, phenyl- · Methylbenzene · Methylbenzol · NCI-C07272 · Phenylmethane · RCRA waste number U220 · Toluol · Tolueen · Toluen · Tolueno · Toluolo · Toulene · monomethyl benzene · phenyl methane · tolu-sol · toluene (sara 313) (cercla)(vp = 22 @ 68f) · toluene (sara 313) (vp: 22 mmgh @ 68f) · toluene (sara iii) · toluene (sara iii) (cercla) (vapor pressure 22 mm hg @ 68f) · toluene (sara iii) (vapor pressure 22 mm hg @ 68f)
Used in cosmetics as an antioxidant and a solvent.
- Antioxidant
- Solvent
- Cleaning agent
- High concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is restricted in EU cosmetics.
Why it's flagged
- Cmr
Toluene is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — restricted
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- In marketed US drugs
- EU Annex III — restricted
- EU restricted in cosmetics
- Found in consumer products
- Cleaning
- Industrial
- View source →restricted
EUEC
Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Nail products Maximum concentration: 25% Conditions of use and warnings: Keep out of reach of children. To be used by adults only CMR: Reprotoxic Cat. 2()
USEPAcommercial use observedEPA CPDat observed this chemical in 21085 composition records across product categories including Furniture and furnishings, Raw materials, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Solvent, Antioxidant, Propellants, non-motive (blowing agents).
- EPA CPDat observed this chemical in 21085 composition records across product categories including Furniture and furnishings, Raw materials, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Solvent, Antioxidant, Propellants, non-motive (blowing agents).Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 3 active drug products and 5 total products.
- FDA NDC lists this ingredient in 3 active drug products and 5 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Toluene. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Toluene yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2013-05-24
- Open →
EPA Chemical and Products Database
exposure · updated october 24, 2019
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2028-05-17
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed Toluene in a product composition. These are source records, not Greenveil catalog products.
Source records
21,085
Named organisations
6
Typical roles