Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
- beauty
- cleaning
- industrial
Tetrahydrofuran
CAS 109-99-9 · 100/100 · High conf.
Also registered as 1 other CAS number
77392-70-2
Concern score
100/100Critical concern driven by cmr.
High confidence
Tetrahydrofuran in plain language
Also known as Oxolane · Thf · 1,4-Epoxybutane · Agrisynth THF · Butane α,δ-oxide · Butane, 1,4-epoxy-
Show all 20 names
Butane, alpha,delta-oxide · Cyclotetramethylene oxide · Furan, tetrahydro- · Furanidine · Hydrofuran · NCI-C60560 · Oxacyclopentane · RCRA waste number U213 · Tetrahydrofuraan · Tetrahydrofuranne · Tetraidrofurano · Tetramethylene oxide · tetrahydrofuran (sara iii) · tetrahydrofuran (cercla)
Used in consumer products as a solvent.
- Solvent
- Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.
Why it's flagged
- Cmr
Tetrahydrofuran is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Beauty
- Cleaning
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()
EUCosIngActiveCosmetics Regulation annex II / ref 1547.
- Cosmetics Regulation annex II / ref 1547.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 699 composition records across product categories including Home maintenance, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Solvent, raw material, elastomeric.
- EPA CPDat observed this chemical in 699 composition records across product categories including Home maintenance, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Solvent, raw material, elastomeric.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Tetrahydrofuran. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Tetrahydrofuran yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2020-07-30
- Open →
EPA Chemical and Products Database
exposure · updated october 27, 2016
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Where it has been recorded
How often EPA CPDat has listed Tetrahydrofuran in a product composition. These are source records, not Greenveil catalog products.
Source records
699
Named organisations
6
Home maintenanceLaboratory suppliesPersonal careSpecialty occupational productsConstruction and building materialsRaw materials
Typical roles
Solvent