Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
- beauty
- industrial
- pharma
Methylphenidate (INN) and its salts
CAS 113-45-1 · 100/100 · High conf.
Also registered as 1 other CAS number
132831-06-2
Concern score
100/100Critical concern based on regulatory listings.
High confidence
Methylphenidate (INN) and its salts in plain language
Also known as Methyl · Methylphenidate · Methyl phenyl(piperidin-2-yl)acetate · Daytrana · Equasym · Nwp 06
Show all 10 names
OROS methylphenidate · Rubifen · Stimdate · α-Phenyl-2-piperidineacetic acid methyl ester
We don't have a plain-language description for Methylphenidate (INN) and its salts yet.
Recorded functional uses: Pharmaceutical
- Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
Why it's flagged
Methylphenidate (INN) and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- In marketed US drugs
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
EUCosIngActiveCosmetics Regulation annex II / ref 175.
- Cosmetics Regulation annex II / ref 175.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 13 active drug products and 17 total products.
- FDA NDC lists this ingredient in 13 active drug products and 17 total products.Source →
Expert safety opinions
No expert opinion on file for Methylphenidate (INN) and its salts. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Methylphenidate (INN) and its salts yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2010-10-20
- Open →
EPA Chemical and Products Database
exposure · updated 2020-08-31
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2027-04-30
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Where it has been recorded
How often FDA National Drug Code directory has listed Methylphenidate (INN) and its salts in a product composition. These are source records, not Greenveil catalog products.
Source records
17
Typical roles
Pharmaceutical
Found in these products
Their ingredient lists include Methylphenidate (INN) and its salts; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
