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Methylene di-t-butylcresol

CAS 119-47-1 · 100/100 · High conf.

Also registered as 18 other CAS numbers

12737-12-1 · 37268-48-7 · 52683-48-4 · 53807-25-3 · 54650-81-6 · 56509-58-1 · 59112-68-4 · 62339-93-9 · 67556-84-7 · 69645-40-5 · 90297-42-0 · 92880-05-2 · 107397-49-9 · 110736-51-1 · 111214-56-3 · 129514-93-8 · 149984-87-2 · 537040-81-6

Methylene di-t-butylcresol chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

Methylene di-t-butylcresol in plain language

What it is

Also known as P-cresol, 2,2'-METHYLENEBIS(6-TERT- butyl- · 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol; · 2,2'-Methylene bis · 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) · 2,2'-BIS(4-METHYL-6-TERT-BUTYLPHENOL)METHANE · 2,2'-METHYLENEBIS(6-(1,1-DIMETHYLETHYL)-4-METHYL)PHENOL

Show all 41 names

2,2'-METHYLENEBIS(6-TERT-BUTYL-P-CRESOL) · 2,2'-METHYLENEBIS(6-TERT.BUTYL-4-METHYL-PHENOL) · 2,2'-Methylenebis(6-tert-butyl-4-methylphenol) · METHYLENEBIS(6-TERT-BUTYL-P-CRESOL), 2,2'- · P-cresol, 2,2'-METHYLENEBIS(6-TERT-BUTYL- · 2,2'-METHYLEN-BIS-(6-TERT-BUTYL-P-KRESOL) · 2,2'-METHYLENE-BIS-(4-METHYL-6-TERT-BUTYLPHENOL) · 2,2'-METHYLENEBIS(4-METHYL-6-TERT-BUTYL phenol) · 2,2'-Methanediylbis(6-tert-butyl-4-methylphenol) · 2,2'-Methylene-bis(4-methyl-6-t-butylphenol) · 6,6'-DI-TERT-BUTYL-4,4'-DIMETHYL-2,2'-METHYLENEDIPHENOL · 6,6'-Di-tert-Butyl-2,2'-Methylenedi-p-cresol · Antioxidant omb · AO 1 (Antioxidant) · Advastab 405 · Alterungsschutzmittel BKF · Anti Ox · Antioxidant 1 · Antioxidant 2246 · Antioxidant BKF · BIS(2-HYDROXY-3-TERT-BUTYL-5-METHYLPHENYL)METHANE · Bisaklofen BP · Calco 2246 · Catolin 14 · Chemanox 21 · Cyanox 2246 · Lowinox 22M46 · Lederle 2246 · Nocrac NS 6 · Plastanox 2246 · Sumilizer MDP · Synox 5lt · Vulkanox bkf · biophenol antioxidant · bisphenol antioxidant

What it does

Used in cosmetics as an antioxidant.

  • Antioxidant
  • Fragrance
Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol;[DBMC] is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1B()

    banned
    View source →
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex II / ref 1682.Source →
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 151 composition records across product categories including Laboratory supplies, Home maintenance, Other direct contact consumer goods. EPA CPDat classifies this chemical for functional uses including Antioxidant, Fragrance, Heat stabilizer.
    • EPA CPDat observed this chemical in 151 composition records across product categories including Laboratory supplies, Home maintenance, Other direct contact consumer goods. EPA CPDat classifies this chemical for functional uses including Antioxidant, Fragrance, Heat stabilizer.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Methylene di-t-butylcresol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Methylene di-t-butylcresol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2022-11-11

    Open →
  • EPA Chemical and Products Database

    exposure · updated November 2014

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Methylene di-t-butylcresol in a product composition. These are source records, not Greenveil catalog products.

Source records

151

Named organisations

6

Laboratory suppliesHome maintenanceOther direct contact consumer goodsRaw materialsVehiclePersonal care

Typical roles

AntioxidantFragrance
See products using Methylene di-t-butylcresol →