Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
CAS 119-47-1 · 100/100 · High conf.
12737-12-1 · 37268-48-7 · 52683-48-4 · 53807-25-3 · 54650-81-6 · 56509-58-1 · 59112-68-4 · 62339-93-9 · 67556-84-7 · 69645-40-5 · 90297-42-0 · 92880-05-2 · 107397-49-9 · 110736-51-1 · 111214-56-3 · 129514-93-8 · 149984-87-2 · 537040-81-6
Concern score
Also known as P-cresol, 2,2'-METHYLENEBIS(6-TERT- butyl- · 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol; · 2,2'-Methylene bis · 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) · 2,2'-BIS(4-METHYL-6-TERT-BUTYLPHENOL)METHANE · 2,2'-METHYLENEBIS(6-(1,1-DIMETHYLETHYL)-4-METHYL)PHENOL
2,2'-METHYLENEBIS(6-TERT-BUTYL-P-CRESOL) · 2,2'-METHYLENEBIS(6-TERT.BUTYL-4-METHYL-PHENOL) · 2,2'-Methylenebis(6-tert-butyl-4-methylphenol) · METHYLENEBIS(6-TERT-BUTYL-P-CRESOL), 2,2'- · P-cresol, 2,2'-METHYLENEBIS(6-TERT-BUTYL- · 2,2'-METHYLEN-BIS-(6-TERT-BUTYL-P-KRESOL) · 2,2'-METHYLENE-BIS-(4-METHYL-6-TERT-BUTYLPHENOL) · 2,2'-METHYLENEBIS(4-METHYL-6-TERT-BUTYL phenol) · 2,2'-Methanediylbis(6-tert-butyl-4-methylphenol) · 2,2'-Methylene-bis(4-methyl-6-t-butylphenol) · 6,6'-DI-TERT-BUTYL-4,4'-DIMETHYL-2,2'-METHYLENEDIPHENOL · 6,6'-Di-tert-Butyl-2,2'-Methylenedi-p-cresol · Antioxidant omb · AO 1 (Antioxidant) · Advastab 405 · Alterungsschutzmittel BKF · Anti Ox · Antioxidant 1 · Antioxidant 2246 · Antioxidant BKF · BIS(2-HYDROXY-3-TERT-BUTYL-5-METHYLPHENYL)METHANE · Bisaklofen BP · Calco 2246 · Catolin 14 · Chemanox 21 · Cyanox 2246 · Lowinox 22M46 · Lederle 2246 · Nocrac NS 6 · Plastanox 2246 · Sumilizer MDP · Synox 5lt · Vulkanox bkf · biophenol antioxidant · bisphenol antioxidant
Used in cosmetics as an antioxidant.
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol;[DBMC] is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Restrictions first, then routine listings from published regulatory sources.
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1B()
No expert opinion on file for Methylene di-t-butylcresol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
No graded research studies for Methylene di-t-butylcresol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
CosIng
regulatory · updated 2026-09-23
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2022-11-11
EPA Chemical and Products Database
exposure · updated November 2014
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
FDA GSRS UNII
registry · updated 2026-02-26
openFDA Substance
registry · updated 2026-05-24
PubChem Live Enrichment
chemistry · updated 2026-05-17
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
How often EPA CPDat has listed Methylene di-t-butylcresol in a product composition. These are source records, not Greenveil catalog products.
Source records
151
Named organisations
6
Typical roles