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Tributyl phosphate

CAS 126-73-8 · 100/100 · High conf.

Also registered as 5 other CAS numbers

15158-85-7 · 19824-61-4 · 80094-39-9 · 329184-61-4 · 1238174-19-0

Tributyl phosphate chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

Tributyl phosphate in plain language

What it is

Also known as Tri-n-butyl phosphate · Tributyl ester phosphoric acid · Butyl phosphate · Butyl phosphate, ((BuO)3PO) · Butyl phosphate, tri- · Calloway 6814

Show all 23 names

Celluphos 4 · Disflamoll TB · Mcs 2495 · Phosphate de tributyle · Phosphoric acid tributyl ester · Tri-N-butylphosphate · Tri-n-butyl phosphate (TNBP) · Tributilfosfato · Tributoxyphosphine oxide · Tributyl ester of phosphoric acid · Tributyle (phosphate de) · Tributylfosfaat · Tributylfosfat · Tributylphosphat · Tributylphosphate · fosfato de tributilo · tbpa

What it does

We don't have a plain-language description for Tributyl phosphate yet.

Recorded functional uses: Defoamer · Flame retardant · Plasticizer

Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

Tributyl phosphate is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial

  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1166.
    • Cosmetics Regulation annex II / ref 1166.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 275 composition records across product categories including Construction and building materials, Specialty occupational products, Vehicle. EPA CPDat classifies this chemical for functional uses including Defoamer, Plasticizer, Flame retardant.
    • EPA CPDat observed this chemical in 275 composition records across product categories including Construction and building materials, Specialty occupational products, Vehicle. EPA CPDat classifies this chemical for functional uses including Defoamer, Plasticizer, Flame retardant.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Tributyl phosphate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Tributyl phosphate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-15

    Open →

  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Tributyl phosphate in a product composition. These are source records, not Greenveil catalog products.

Source records

275

Named organisations

6

Construction and building materialsSpecialty occupational productsVehicleLaboratory suppliesElectronics/small appliancesMedical/dental

Typical roles

DefoamerFlame retardantPlasticizer
See products using Tributyl phosphate →