# SODIUM HYDROXIDE URL: https://app.greenveil.ai/ingredients/ingredient_cas_1310_58_3 Categories: beauty, cleaning, industrial, pharma Functions: Binder, Catalyst, Cleaning agent, Fragrance, Oxidizing agent, Processing aids not otherwise specified, Stabilizing agent, Surfactant (surface active agent), alkalinizing agent, chemical peel, pH balancer, pH regulating agent Identifier: 1310-58-3 > SODIUM HYDROXIDE is used as binder / catalyst. Greenveil chemical-concern score: 70/100 — High concern based on regulatory listings.. Assessed from 180 sources. ## Safety assessment - Chemical concern score: 70/100 — High concern based on regulatory listings. - Confidence: 4 - Rationale: Potassium or sodium hydroxide is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009. ## Regulatory status - EU: restricted — Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Nail cuticle solvent (b) Hair straightener (c) pH adjuster for depilatories (d) Other uses as pH adjuster Callosity softener/remover (entry 15d) Maximum concentration: (a) 5% (b) 2% (General use) and 4.5% (Professional use) Entry 15d: 1,5% Other conditions: (b) 1. General use 2. Professional use (c) up to pH 12.7 (d) up to pH 11 15 d Contains alcakali, Avoid contact with eyes Keep out of reach of chindren ans Read directions for use carefully Conditions of use and warnings: (a) Contains alkali Avoid contact with eyes Can cause blindness Keep out of reach of children (b) 1. Contains alkali Avoid contact with eyes Can cause blindness Keep out of reach of children 2. For professional use only Avoid contact with eyes Can cause blindness (c) Keep out of reach of children Avoid contact with eyes - US: commercial use observed — EPA CPDat observed this chemical in 11688 composition records across product categories including Construction and building materials, Raw materials, Home maintenance. EPA CPDat classifies this chemical for functional uses including pH regulating agent, pH balancer, alkalinizing agent. - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Potency: ADJ PH - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE; Potency: 60 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, COATED; Potency: 0.08 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, COATED PELLETS; Potency: 0.01 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Potency: 0.25 mg - US: inactive ingredient database — Route: AURICULAR (OTIC); Dosage form: SOLUTION; Potency: 0.8 %w/w - US: inactive ingredient database — Route: AURICULAR (OTIC); Dosage form: SOLUTION/ DROPS; Potency: ADJ PH - US: inactive ingredient database — Route: AURICULAR (OTIC); Dosage form: SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: AURICULAR (OTIC); Dosage form: SUSPENSION/ DROPS; Potency: ADJ PH - US: inactive ingredient database — Route: BUCCAL; Dosage form: FILM; Potency: 0.09 mg - US: inactive ingredient database — Route: BUCCAL; Dosage form: FILM, SOLUBLE; Maximum daily exposure: 5 mg - US: inactive ingredient database — Route: BUCCAL; Dosage form: MOUTHWASH; Potency: 2 mg/1ml - US: inactive ingredient database — Route: DENTAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: DENTAL; Dosage form: PASTE; Potency: 0.6 %w/w - US: inactive ingredient database — Route: DENTAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: ENDOTRACHEAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: ENDOTRACHEAL; Dosage form: POWDER, FOR SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: ENDOTRACHEAL; Dosage form: SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: EPIDURAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: EPIDURAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: EPIDURAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: EXTRACORPOREAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INFILTRATION; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INFILTRATION; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTERSTITIAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-AMNIOTIC; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTERIAL; Dosage form: INJECTION; Potency: 176 mg - US: inactive ingredient database — Route: INTRA-ARTERIAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTERIAL; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTERIAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTERIAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTICULAR; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTICULAR; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTICULAR; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRA-ARTICULAR; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: ADJ PH - US: inactive ingredient database — Route: INTRABURSAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRACARDIAC; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRACAUDAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRACAUDAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRACAVERNOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRACAVITARY; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRACAVITARY; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRADERMAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRADERMAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRADERMAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: ADJ PH - US: inactive ingredient database — Route: INTRADISCAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRALESIONAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRALESIONAL; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRALESIONAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 176 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 7.01 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 0.35 %w/v - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 78 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 27 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: LIQUID; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: 5.4 mg - US: inactive ingredient database — Route: INTRAOCULAR; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAPERITONEAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAPERITONEAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAPLEURAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRASPINAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRASYNOVIAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRASYNOVIAL; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRASYNOVIAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: ADJ PH - US: inactive ingredient database — Route: INTRATHECAL; Dosage form: INJECTION; Potency: 176 mg - US: inactive ingredient database — Route: INTRATHECAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRATHECAL; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRATHECAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRATHECAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRATUMOR; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRATUMOR; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVASCULAR; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVASCULAR; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVASCULAR; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTABLE, LIPOSOMAL; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 456 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, EMULSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 136.55 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 78.36 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 78 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SUSPENSION, LIPOSOMAL; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: LIQUID; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: POWDER; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: SOLUTION; Potency: 2.78 %w/v - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: SOLUTION, CONCENTRATE; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVESICAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVITREAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: INTRAVITREAL; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: IONTOPHORESIS; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: IRRIGATION; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: NASAL; Dosage form: SOLUTION; Potency: 20 mg - US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY; Potency: ADJ PH - US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY, METERED; Potency: ADJ PH - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: DROPS; Potency: NA - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: EMULSION; Potency: 0.02 %w/v - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: GEL; Maximum daily exposure: 6 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, LIQUID FILLED; Potency: 1.5 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CONCENTRATE; Potency: 10 mg/5ml - US: inactive ingredient database — Route: ORAL; Dosage form: ELIXIR; Potency: ADJ PH - US: inactive ingredient database — Route: ORAL; Dosage form: EMULSION; Potency: ADJ PH - US: inactive ingredient database — Route: ORAL; Dosage form: FILM, SOLUBLE; Maximum daily exposure: 11 mg - US: inactive ingredient database — Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: ORAL; Dosage form: LIQUID; Potency: 2 mg/5ml - US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 9 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 9120 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION; Potency: 400 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SYRUP; Potency: 71 mg/5ml - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 10 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, COATED; Potency: NA - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 4 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 13 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 8 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Maximum daily exposure: 1 mg - US: inactive ingredient database — Route: PARENTERAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: PARENTERAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: PARENTERAL; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: PARENTERAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: PERIDURAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: PERINEURAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: PERIODONTAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: RECTAL; Dosage form: ENEMA; Potency: 0.44 %v/v - US: inactive ingredient database — Route: RECTAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: RECTAL; Dosage form: SOLUTION; Potency: NA - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: AEROSOL, METERED; Potency: ADJ PH - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: POWDER; Potency: ADJ PH - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: SOLUTION; Potency: 8 %w/v - US: inactive ingredient database — Route: RETROBULBAR; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: SOFT TISSUE; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: SOFT TISSUE; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBARACHNOID; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCONJUNCTIVAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION; Potency: 31.45 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Potency: 1 %w/v - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: SUSPENSION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: NA - US: inactive ingredient database — Route: SUBMUCOSAL; Dosage form: INJECTION; Potency: ADJ PH - US: inactive ingredient database — Route: SUBMUCOSAL; Dosage form: INJECTION, SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: AEROSOL, FOAM; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 69 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM, AUGMENTED; Maximum daily exposure: 6 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: DISC; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: EMULSION; Potency: 0.2 %w/w - US: inactive ingredient database — Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 20 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: JELLY; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: LIQUID; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 21 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION, AUGMENTED; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: OINTMENT; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: OINTMENT, AUGMENTED; Potency: 0.11 %w/w - US: inactive ingredient database — Route: TOPICAL; Dosage form: SHAMPOO; Maximum daily exposure: 3 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION; Maximum daily exposure: 39 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION/ DROPS; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: SPONGE; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: SUSPENSION/ DROPS; Potency: ADJ PH - US: inactive ingredient database — Route: TOPICAL; Dosage form: SWAB; Potency: 0.01 %w/w - US: inactive ingredient database — Route: TRANSDERMAL; Dosage form: FILM, EXTENDED RELEASE; Potency: 0.85 mg - US: inactive ingredient database — Route: TRANSDERMAL; Dosage form: GEL; Maximum daily exposure: 350 mg - US: inactive ingredient database — Route: TRANSDERMAL; Dosage form: GEL, METERED; Maximum daily exposure: 350 mg - US: inactive ingredient database — Route: URETERAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: URETHRAL; Dosage form: SOLUTION; Potency: ADJ PH - US: inactive ingredient database — Route: VAGINAL; Dosage form: CREAM; Potency: 0.19 %w/w - US: inactive ingredient database — Route: VAGINAL; Dosage form: GEL; Maximum daily exposure: 20 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.05 %w/v - US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical. - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: ADJ PH _Assessed by Greenveil._