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2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL

CAS 131657-78-8 · 70/100 · High conf.

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL chemical structure

Concern score

70/100High concern based on regulatory listings.
High confidence

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL in plain language

What it is

Also known as Phenol, 2-Chloro-6-(ethylamino)-4-nitro- (see note 17) · Phenol, 2-Chloro-6-(ethylamino)-4-nitro- and its salts · 2-Chloro-6-(ethylamino)-4-nitrophenol · 2-chloranyl-6-(ethylamino)-4-nitro-phenol · 6-Chloro-2-(ethylamino)-4-nitrophenol · AKOS015891346

Show all 15 names

BS-49681 · Cdfnusaxzdsxkf-uhfffaoysa-n · CS-0151978 · D94862 · DB-062839 · Ec 411-440-1 · F232684 · Phenol, 2-chloro-6-(ethylamino)-4-nitro- · UNII-5LIV96LADQ

What it does

Used in cosmetics as a hair dye.

  • Hair dyeing
  • Colourant
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

Phenol, 2-Chloro-6-(ethylamino)-4-nitro- (see note 17) is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUCosIngActive3 entries
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Dye.
    • EPA CPDat observed this chemical in 2 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Dye.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2014-06-05

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL in a product composition. These are source records, not Greenveil catalog products.

Source records

2

Named organisations

1

Personal care

Typical roles

Hair dyeingColourant
See products using 2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL →