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Zinc pyrithione

CAS 13463-41-7 · 100/100 · High conf.

Also registered as 35 other CAS numbers

1192-70-7 · 1320-68-9 · 3138-01-0 · 3590-23-6 · 3865-77-8 · 14376-32-0 · 15686-64-3 · 16782-00-6 · 17652-47-0 · 31089-48-2 · 35430-20-7 · 39412-61-8 · 51148-10-8 · 51406-57-6 · 55172-61-7 · 74261-71-5 · 109702-19-4 · 118480-78-7 · 162400-43-3 · 186322-74-7 · 192458-89-2 · 208398-70-3 · 226883-65-4 · 244778-79-8 · 266692-38-0 · 318995-78-7 · 943428-71-5 · 1021487-49-9 · 1199553-62-2 · 1323439-04-8 · 1428553-54-1 · 1698050-37-1 · 2173031-33-7 · 2218447-38-0 · 2259655-38-2

Zinc pyrithione chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Zinc pyrithione in plain language

What it is

Also known as Pyrithione zinc · Pyrithione zinc derivative · Zinc pyrithone · Zinc omadine · Zinc pyridinethione · Zinc, BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO-O,S)-(T-4)-

Show all 43 names

Zincpolyanemine · zinc bis(1-oxidopyridin-1-ium-2-thiolate) · 1-HYDROXY-2-PYRIDINTHION-ZN(II)-SALZ · 1-Hydroxy-2-pyridinethione, zinc salt · 2-Mercaptopyridine 1-oxide zinc salt · 2-Pyridinethiol 1-oxide zinc salt · 2-Pyridinethiol N-oxide zinc salt · BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO)ZINC · Balancing · Biocut ZP · Chevance · Dandrene · Dandruff · Elementz · Evafine P 50 · Finecide ZPT · Head & shoulders conditioner · Hokucide ZPT · Medaclear · Niccanon SKT · Pyridine-2-thiol-1-oxide, zinc complex (2:1) · Sebulon shampoo · Tomicide Z 50 · Tomicide ZPT 50 · Vegetability · ZINC-2-PYRIDINETHIONE-1-OXIDE · Zinc pt · Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)- · Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)- · biokera · bis(N-oxopyridine-2-thionato)zinc (II) · pyrithione zinc (anti-dandruff agent) · pyrithione zinc 1% · pyrithione zinc 1% w/w · shampoo · zinc pyrithion (2 % w/w) · zinc pyrithione (zpt)

What it does

Used in cosmetics as a preservative, an anti-seborrheic and an anti-sebum. Zinc Pyrithione is the aromatic zinc compound.

  • Preservative
  • Anti-seborrheic
  • Anti-sebum
  • Hair conditioning
  • Conditioner
  • Anti-dandruff
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Pyrithione zinc; (T-4)- bis[1-(hydroxy-.kappa.O)pyridine-2(1H)- thionato-.kappa.S]zinc is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • In marketed US drugs
  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial

  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex II / ref 1670.Source →
    • Zinc Pyrithione is the aromatic zinc compound Restriction: Annex II/1670Source →
  • USFDAmarketed drug occurrence2 entries
    • FDA NDC lists this ingredient in 309 active drug products and 322 total products.Source →
    • FDA NDC lists this ingredient in 10 active drug products and 10 total products.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 367 composition records across product categories including Construction and building materials, Furniture and furnishings, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Softener and conditioner, Anti-dandruff.
    • EPA CPDat observed this chemical in 367 composition records across product categories including Construction and building materials, Furniture and furnishings, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Softener and conditioner, Anti-dandruff.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Zinc pyrithione. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Zinc pyrithione yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2021-11-03

    Open →

  • EPA Chemical and Products Database

    exposure · updated september 29, 2015

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)
Openfda substance

pesticideinfo.org

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Zinc pyrithione in a product composition. These are source records, not Greenveil catalog products.

Source records

367

Named organisations

6

Construction and building materialsFurniture and furnishingsCleaning and safetyPersonal careRaw materialsHome maintenance

Typical roles

PreservativeAnti-seborrheicAnti-sebumHair conditioningConditionerAnti-dandruff
See products using Zinc pyrithione →

Catalog

Found in these products

Their ingredient lists include Zinc pyrithione; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 123 →Find products without it →