Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
- beauty
- industrial
SH-POLYPEPTIDE-123
CAS 1375784-79-4
Concern score
Not assessed — no hazard data yet.
SH-POLYPEPTIDE-123 in plain language
Also known as Collagen (recombinant human pPIC9KG6) · Reallagen collagen
Used in cosmetics as a skin protectant.
- Skin protecting
- Humectant
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
Regulation
No restrictions found. SH-POLYPEPTIDE-123 appears in these published regulatory listings.
- Found in consumer products
- Industrial
EUCosIngActivesh-Polypeptide-123 is a single chain recombinant human peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized to be similar to the human gene which codes for Collagen Alpha-1 (III) Chain used as such or adapted to the production host. It contains a maximum of 1466 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of all or part of the 20 standard amino acids.
- sh-Polypeptide-123 is a single chain recombinant human peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized to be similar to the human gene which codes for Collagen Alpha-1 (III) Chain used as such or adapted to the production host. It contains a maximum of 1466 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of all or part of the 20 standard amino acids.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Humectant.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as protein.
- openFDA substance registry classifies this ingredient as protein.Source →
Expert safety opinions
No expert opinion on file for SH-POLYPEPTIDE-123. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for SH-POLYPEPTIDE-123 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
No signal in this context
Where it has been recorded
How often EPA CPDat has listed SH-POLYPEPTIDE-123 in a product composition. These are source records, not Greenveil catalog products.
Named organisations
1
Typical roles
Skin protectingHumectant