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Annatto

CAS 1393-63-1 · 40/100 · High conf.

Also registered as 5 other CAS numbers

1343-85-7 · 8015-67-6 · 79586-44-0 · 542-40-5 · 6983-79-5

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Annatto in plain language

What it is

On cosmetic ingredient lists it appears as “CI 75120”.

Also known as CI 75120 · Annatto extract · Annatto extracts · Annatto e · L. orange · Orlean

Show all 33 names

Terre orellana · Annatto seed powder · Annatto a 640 · Annotta · Bixa orellana seed carotenoids · C orange 12 · C.I. 75120 · C.I. natural orange 4 · CI (1975) 75120 (natural orange 4) · E 160B · E-160B(I) · E-160B(II) · Ins NO.160B(I) · Ins NO.160B(II) · INS-160B(I) · INS-160B(II) · San annatto 2380 · 6,6'-Diapo-psi.,psi.-carotenedioic acid · Annatto, extract (bixa orellana l.) · Annatto coloring dye · Annatto seed (Bixa orellana L.) · Annatto; 6,6'-Diapo-psi.,psi.-carotenedioic acid · Annotta extract · C.I. Natural Orange C · E160B · annatto(bixin) · bixa orellana extract

What it does

Used in cosmetics as a colourant. CI 75120 is the coloring matter from the seeds of Bixa orellana.

  • Colorant
  • Colour
  • Colourant
  • Fragrance
  • Flavouring
  • Conditioner
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — Annatto appears on published "allowed" regulatory lists rather than on a restriction list.

Annatto is listed in Annex IV of the EU Cosmetics Regulation (EC) 1223/2009 (colorants allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Annatto appears in these published regulatory listings.

  • EU Annex IV — permitted colorant
  • EU permitted colorant

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex IV / ref 109.Source →
    • CI 75120 is the coloring matter from the seeds of Bixa orellana. Restriction: IV/109Source →
  • USFDAlisted in openFDA substance2 entries
    • openFDA substance registry classifies this ingredient as structurallydiverse.Source →
    • openFDA substance registry classifies this ingredient as concept.Source →
  • EUECallowed_listedAnnex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Conditions of use and warnings: Purity criteria as set out in Commission Directive 95/45/EC (E 160b)
    • Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Conditions of use and warnings: Purity criteria as set out in Commission Directive 95/45/EC (E 160b)Source →
  • GLOBALJECFABIXIN: 0-12 mg/kg bw; NORBIXIN AND ITS SODIUM AND POTASSIUM SALT: 0-0.6 mg/kg bw (group ADI, expressed as norbixin)JECFA evaluation lists ADI BIXIN: 0-12 mg/kg bw; NORBIXIN AND ITS SODIUM AND POTASSIUM SALT: 0-0.6 mg/kg bw (group ADI, expressed as norbixin). Functional class: colour.
    • JECFA evaluation lists ADI BIXIN: 0-12 mg/kg bw; NORBIXIN AND ITS SODIUM AND POTASSIUM SALT: 0-0.6 mg/kg bw (group ADI, expressed as norbixin). Functional class: colour.Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 64 composition records across product categories including Home maintenance, Medical/dental, Personal care. EPA CPDat classifies this chemical for functional uses including Dye, Fragrance, Deodorizer.
    • EPA CPDat observed this chemical in 64 composition records across product categories including Home maintenance, Medical/dental, Personal care. EPA CPDat classifies this chemical for functional uses including Dye, Fragrance, Deodorizer.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI BIXIN: 0-12 mg/kg bw; NORBIXIN AND ITS SODIUM AND POTASSIUM SALT: 0-0.6 mg/kg bw (group ADI, expressed as norbixin). Functional class: colour.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Annatto yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2020-08-14

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

  • SoyContains · Oral (ingested)

    Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Annatto in a product composition. These are source records, not Greenveil catalog products.

Source records

64

Named organisations

6

Home maintenanceMedical/dentalPersonal care

Typical roles

ColorantColourColourantFragranceFlavouringConditioner
See products using Annatto →

Catalog

Found in these products

Their ingredient lists include Annatto; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 17 →Find products without it →