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4,4'-Thiodianiline

CAS 139-65-1 · 100/100 · High conf.

4,4'-Thiodianiline chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

4,4'-Thiodianiline in plain language

What it is

Also known as 4,4'-Thiodianiline and its salts · 4,4'-Sulfanediyldianiline · 4-(4-aminophenyl)sulfanylaniline · Baps · Bis(p-aminophenyl) sulfide · Di(p-aminophenyl) sulfide

Show all 26 names

P,p'-diaminodiphenyl sulfide · 4,4'-Diaminodiphenyl sulfide · 4,4'-Diaminodiphenylsulfide · 4,4'-Diaminophenyl sulfide · 4,4'-THIOBISBENZENAMINE · 4,4'-Thioaniline · 4,4'-Thiobis(aniline) · 4,4-thiodianiline · Aniline, 4,4'-thiodi- · Benzenamine, 4,4'-thiobis- · Bis(4-aminophenyl) sulfide · Bis(4-aminophenyl)sulphide · Bis(p-aminophenyl)sulphide · Bis(para-aminophenyl)sulphide · Di(p-aminophenyl)sulphide · NCI-C01707 · Sulfide, bis(p-aminophenyl) · Thioaniline · Thiodi-p-phenylenediamine · p,p-Thiodianiline

What it does

We don't have a plain-language description for 4,4'-Thiodianiline yet.

Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

4,4'-Thiodianiline and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1B()

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1159.
    • Cosmetics Regulation annex II / ref 1159.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including Furniture and furnishings.
    • EPA CPDat observed this chemical in 1 composition records across product categories including Furniture and furnishings.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 4,4'-Thiodianiline. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 4,4'-Thiodianiline yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-15

    Open →
  • EPA Chemical and Products Database

    exposure · updated March 8, 2019

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 4,4'-Thiodianiline in a product composition. These are source records, not Greenveil catalog products.

Source records

1

Named organisations

5

Furniture and furnishings
See products using 4,4'-Thiodianiline →