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Pentasodium pentetate

CAS 59232-96-1 · 100/100 · High conf.

Also registered as 2 other CAS numbers

81647-97-4 · 140-01-2

Pentasodium pentetate chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Pentasodium pentetate in plain language

What it is

Also known as Pentetate pentasodium · Diethylenetriaminepentaacetic acid pentasodium salt · Pentasodium diethylenetriaminepentaacetate · Pentasodium dtpa · Caswell No. 642B · Chel 330

Show all 23 names

Chelest P · Clewat DP 80 · Diaethylentriamin-pentaessigsaeure-na-salz · Dissolvine d 40K · Dissolvine d 50 · Detarex PY · Diethylenetriamine pentaacetic acid pentasodium salt · Dtpa pentasodium salt · Hamp-ex 80 · Kiresuto P · Perma kleer 140 · Plexene d · Syntron c · Sodium diethylenetriaminepentaacetate · Tetralon b · Trilon c · Versenex 80

What it does

Used in cosmetics as a chelating agent. Pentasodium Pentetate is the pentasodium salt of diethylenetriaminepentaacetic acid.

  • Chelating
  • Chelating agent
  • Thickener
  • Cleaning agent
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)tetraacetate; Pentasodium Pentetate (INCI) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial

  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActive2 entries
    • Pentasodium Pentetate is the pentasodium salt of diethylenetriaminepentaacetic acid. It conforms to the formula: Restriction: II / 1721Source →
    • Cosmetics Regulation annex II / ref 1721.Source →
  • USFDAinactive ingredient database2 entries — 2 administration routes
    • Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 5 mgSource →
    • Route: TOPICAL; Dosage form: SOAP; Potency: NASource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1495 composition records across product categories including Specialty occupational products, Medical/dental, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Chelating agent, Thickening agent, Cleaning agent.
    • EPA CPDat observed this chemical in 1495 composition records across product categories including Specialty occupational products, Medical/dental, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Chelating agent, Thickening agent, Cleaning agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Pentasodium pentetate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Pentasodium pentetate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2023-08-24

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Pentasodium pentetate in a product composition. These are source records, not Greenveil catalog products.

Source records

1,495

Named organisations

6

Specialty occupational productsMedical/dentalLaboratory suppliesBatteriesConstruction and building materialsPersonal care

Typical roles

ChelatingChelating agentThickenerCleaning agent
See products using Pentasodium pentetate →

Catalog

Found in these products

Their ingredient lists include Pentasodium pentetate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 53 →Find products without it →