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Diethyl maleate, when used as a fragrance ingredient

CAS 141-05-9 · 100/100 · High conf.

Diethyl maleate, when used as a fragrance ingredient chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Diethyl maleate, when used as a fragrance ingredient in plain language

What it is

Also known as Diethyl maleate · (2Z)-2-BUTENEDIOIC acid, 1,4-DIETHYL ester · Diethyl (2Z)-but-2-enedioate · Diethyl ester maleic acid · diethyl (Z)-but-2-enedioate · (2Z)-2-Butenedioic acid diethyl ester

Show all 20 names

(Z)-2-Butenedioic acid diethyl ester · 2-Butenedioic acid (2Z)-, 1,4-diethyl ester · 2-Butenedioic acid (2Z)-, diethyl ester · 2-Butenedioic acid (Z)-, diethyl ester · 2-Butenedioic acid, diethyl ester, (2Z)- · 2-Butenedioic acid, diethyl ester, (Z)- · Diethyl (2E)-2-butenedioate · Diethyl (Z)-2-butenedioate · Diethylester kyseliny maleinove · Diethylmaleat · Diethylmaleate · Ethyl maleate · Staflex dem · diethyl maleic acid diester

What it does

Used in consumer products as a fragrance ingredient and a flavouring.

  • Fragrance
  • Flavouring
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Diethyl maleate, when used as a fragrance ingredient is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 426.
    • Cosmetics Regulation annex II / ref 426.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient, Fragrance.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Flavouring and nutrient, Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Diethyl maleate, when used as a fragrance ingredient. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Diethyl maleate, when used as a fragrance ingredient yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-20

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2022-06-22

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Diethyl maleate, when used as a fragrance ingredient in a product composition. These are source records, not Greenveil catalog products.

Named organisations

3

Typical roles

FragranceFlavouring
See products using Diethyl maleate, when used as a fragrance ingredient →