Hexetidine

Hexetidine in plain language

What it is

Also known as 5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl- · 1,3-Bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine · 5-AMINO-1,3-BIS(2-ETHYLHEXYL)HEXAHYDRO-5-METHYLPYRIMIDINE · 5-Amino-1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidine · A01AB12 · Caswell No. 033BB

Show all 21 names

Collu hextril · Duranil · Duranil Aerosol · Elsix · Esetidina · Glypesin · Hexetidina · Hexetidinum · Hexigel · Hexoral · Hextril · Oraldene · Oraldine · Sterisil · Steri-sol

What it does

Used in cosmetics as a preservative, an antimicrobial and an oral-care ingredient. Hexetidine is the heterocyclic organic compound.

• Preservative
• Antimicrobial
• Oral care

Is it a concern?

Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — Hexetidine appears on published "allowed" regulatory lists rather than on a restriction list.

5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl- is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex V — permitted preservative
• EU permitted preservative

• EU·CosIng·Active2 entries

  • Cosmetics Regulation annex V / ref 19.Source →
  • Hexetidine is the heterocyclic organic compound that conforms to the formula: Restriction: V/19Source →
• EU·EC·allowed_listedAnnex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.1%

  • Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.1%Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Preservative, oral care.

  • EPA CPDat observed this chemical in 1 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Preservative, oral care.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Hexetidine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.