- beauty
- industrial
Phoxim
CAS 14816-18-3 · 100/100 · High conf.
Also registered as 3 other CAS numbers
29556-99-8 · 35915-13-0 · 1195303-43-5
Concern score
100/100Critical concern driven by cmr.
High confidence
Phoxim in plain language
Also known as BAY-77488 · N-diethoxyphosphinothioyloxybenzenecarboximidoyl cyanide · Phoxime · Bay 77488 · Bayer 9053 · Baythion
Show all 18 names
Glyoxylonitrile, phenyl-, oxime O,O-diethyl phosphorothioate · O,O-Diethyl O-(α-cyanobenzylideneamino) phosphorothioate · O,O-Diethyl-alpha-cyanobenzylidineaminooxyphosphonothiate · O-diethyl phosphorothioate phenylglyoxylnitrile oxime o · O-diethyl phosphorothioate Phenylglyoxylonitrile oxime O · Phoxim (ISO) · Phoxin · Sebacil (insecticide) · Sebacil Pour-on · Valexon · Volaton · O-diethylphosphorothioate phenylglyoxylonitrile oxime O
We don't have a plain-language description for Phoxim yet.
- Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.
Why it's flagged
- Cmr
Phoxim (ISO); a-(diethoxy-phosphinothioylimino) phenylacetonitrile is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 2()
EUCosIngActiveCosmetics Regulation annex II / ref 1410.
- Cosmetics Regulation annex II / ref 1410.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Phoxim. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Phoxim yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2020-07-30
- Open →
EPA Chemical and Products Database
exposure · updated 4 December 2007
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (2)
pubs.acs.org
Allergen profile
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
- SoyContains · Oral (ingested)
Source: chemindex_name_match
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed Phoxim in a product composition. These are source records, not Greenveil catalog products.
Named organisations
4