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2,2'-Methylenebis(6-bromo-4-chlorophenol)

CAS 15435-29-7 · 20/100 · High conf.

Also registered as 1 other CAS number

81410-50-6

2,2'-Methylenebis(6-bromo-4-chlorophenol) chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

2,2'-Methylenebis(6-bromo-4-chlorophenol) in plain language

What it is

On cosmetic ingredient lists it appears as “Bromochlorophene”.

Also known as Bromochlorophene · Bromchlorophen · Bromchlorophene · Bromochlorofen · Bromochlorophen · 6,6'-DIBROM-4,4'-DICHLOR-2,2'-METHYLENDIPHENOL

Show all 13 names

Brophen · 3,3'-Dibromo-5,5'-dichloro-2,2'-dihydroxydiphenylmethane · 3,3-Dibromo-5,5-dichloro-2,2-dihydroxy-diphenylmethane · 3,3-Dibromo-5,5-dichloro-2,2-dihydroxydiphenylmethane · 6,6'-METHYLENEBIS(2-BROMO-4-CHLOROPHENOL) · 6,6-Dibromo-4,4-dichloro-2,2'-methylene-diphenol · Bis(3-bromo-5-chloro-2-hydroxyphenyl)methane

What it does

Used in cosmetics as a preservative, an antimicrobial and a deodorant. Bromochlorophene is the halogenated aromatic compound.

  • Preservative
  • Antimicrobial
  • Deodorant
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — 2,2'-Methylenebis(6-bromo-4-chlorophenol) appears on published "allowed" regulatory lists rather than on a restriction list.

2,2'-Methylenebis(6-bromo-4-chlorophenol) is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. 2,2'-Methylenebis(6-bromo-4-chlorophenol) appears in these published regulatory listings.

  • EU Annex V — permitted preservative
  • EU permitted preservative

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex V / ref 37.Source →
    • Bromochlorophene is the halogenated aromatic compound that conforms to the formula: Restriction: V/37Source →
  • EUECallowed_listedAnnex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.1%
    • Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.1%Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Biocide, Preservative, Deodorizer.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Biocide, Preservative, Deodorizer.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 2,2'-Methylenebis(6-bromo-4-chlorophenol). These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 2,2'-Methylenebis(6-bromo-4-chlorophenol) yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-25

    Open →
  • EPA Chemical and Products Database

    exposure · updated 4 December 2007

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

chemicalregister.com

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 2,2'-Methylenebis(6-bromo-4-chlorophenol) in a product composition. These are source records, not Greenveil catalog products.

Named organisations

2

Typical roles

PreservativeAntimicrobialDeodorant
See products using 2,2'-Methylenebis(6-bromo-4-chlorophenol) →

Catalog

Found in these products

Cosmetic and personal-care products that list 2,2'-Methylenebis(6-bromo-4-chlorophenol) are shown first. Their ingredient lists include 2,2'-Methylenebis(6-bromo-4-chlorophenol); each product's own rating depends on its whole formula, so it is shown on the product page, not here.