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Trifluralin

CAS 1582-09-8 · 100/100 · High conf.

Also registered as 5 other CAS numbers

39300-53-3 · 52627-52-8 · 61373-95-3 · 71281-30-6 · 75635-23-3

Trifluralin chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

Trifluralin in plain language

What it is

Also known as 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline · 2,6-Dinitro-4-(trifluoromethyl)-N,N-dipropylaniline · 2,6-Dinitro-N,N-di-n-propyl-α,α,α-trifluoro-p-toluidine · 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine · 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine · 4-(Di-n-propylamino)-3,5-dinitro-1-(trifluoromethyl)benzene

Show all 30 names

4-(Trifluoromethyl)-2,6-dinitro-N,N-dipropylaniline · Agreflan · Benzenamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- · Crisalin · Crisalina · Digermin · Elancolan · Ipersan · Nitran · Nitran K · Olitref · Super-Treflan · Synfloran · Trefanocide · Treficon · Treflan · Trifluralin (ISO) · Trifluraline · Triflurex · Trifurex · Trikepin · Tristar · trifluralin (sara iii) · triflurallin

What it does

Used in consumer products as an antimicrobial.

  • Antimicrobial
Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

Trifluralin (ISO); a,a,a-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine; 2,6-dinitro-N,N-dipropyl-4-trifluoromethylaniline; N,N-dipropyl-2,6-dinitro-4-trifluoromethylaniline is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1498.
    • Cosmetics Regulation annex II / ref 1498.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 23 composition records across product categories including Laboratory supplies, Landscape/yard, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Biocide, Degradant/impurity.
    • EPA CPDat observed this chemical in 23 composition records across product categories including Laboratory supplies, Landscape/yard, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Biocide, Degradant/impurity.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Trifluralin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Trifluralin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2020-07-30

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 1997

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Trifluralin in a product composition. These are source records, not Greenveil catalog products.

Source records

23

Named organisations

6

Laboratory suppliesLandscape/yardCleaning products and household careFood and drug

Typical roles

Antimicrobial
See products using Trifluralin →