CI 45396

CI 45396 in plain language

What it is

Also known as 4',5'-DINITROFLUORESCEIN · Solvent orange 16 · 2-(6-HYDROXY-4,5-DINITRO-3-OXO-3H-XANTHEN-9-YL)BENZOIC acid · AKOS015889396 · ALBB-036603 · Rycibgacbraxbm-uhfffaoysa-n

Show all 7 names

UNII-43N83DU7RA

What it does

Used in cosmetics as a colourant. CI 45396 is classed chemically as a xanthene colour.

• Colorant
• Colourant

Is it a concern?

Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — CI 45396 appears on published "allowed" regulatory lists rather than on a restriction list.

3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one is listed in Annex IV of the EU Cosmetics Regulation (EC) 1223/2009 (colorants allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex IV — permitted colorant
• EU permitted colorant

• EU·CosIng·Active2 entries

  • Cosmetics Regulation annex IV / ref 77.Source →
  • CI 45396 is classed chemically as a xanthene colour. It conforms to the formula: Restriction: IV/77Source →
• EU·EC·allowed_listedAnnex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Other conditions: 1%, when used in lip products Conditions of use and warnings: Only in free acid form, when used in lip products

  • Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Other conditions: 1%, when used in lip products Conditions of use and warnings: Only in free acid form, when used in lip productsSource →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.

  • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for CI 45396. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.