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2-(4-Amino-3-nitroanilino)ethanol

CAS 24905-87-1 · 70/100 · High conf.

2-(4-Amino-3-nitroanilino)ethanol chemical structure

Concern score

70/100High concern based on regulatory listings.
High confidence

2-(4-Amino-3-nitroanilino)ethanol in plain language

What it is

On cosmetic ingredient lists it appears as “Hc red no. 7”.

Also known as Hc red no. 7 · HC Red 7 · Hc red no 7 · 2-(4-Amino-3-nitroanilino)ethan-1-ol · 2-((4-AMINO-3-NITROPHENYL)AMINO)ETHANOL · 2-(4-amino-3-nitro-anilino)ethanol

Show all 14 names

2-AMINO-5-(2-HYDROXYETHYLAMINO)NITROBENZENE · 2-NITRO-4-(.BETA.-HYDROXYETHYLAMINO)ANILINE · AKOS006273073 · Colorex HCR7 · Dagcjjzwdavkre-uhfffaoysa-n · Ethanol, 2-(4-AMINO-3-NITROANILINO)- · Imexine fz · UNII-5WRI22G12X

What it does

Used in cosmetics as a hair dye. HC Red No. 7 is the hair color.

  • Hair dyeing
  • Colourant
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

2-(4-Amino-3-nitroanilino)ethanol is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Hair dye substance in non-oxidative hair dye products Maximum concentration: 1,0% Other conditions: - Do not use with nitrosating agents - Maximum notrosamine content: 50 micrograme/Kg - Keep in nitrite-free containers Conditions of use and warnings: Hair colorants can cause severe allergic reactions

    restricted
    View source →
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex III / ref 251.Source →
    • HC Red No. 7 is the hair color that conforms to the formula Restriction: Annex III/251Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 2-(4-Amino-3-nitroanilino)ethanol. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 2-(4-Amino-3-nitroanilino)ethanol yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2013-09-09

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.