# METHYLISOTHIAZOLINONE

URL: https://app.greenveil.ai/ingredients/ingredient_cas_26172_55_4
Categories: beauty, cleaning, food, industrial, pharma
Functions: preservative, Antioxidant, Biocide, Fragrance, Preservative, Processing aids not otherwise specified
Identifier: 26172-55-4

> METHYLISOTHIAZOLINONE is used as preservative / antioxidant. Greenveil chemical-concern score: 25/100 — Minor concern based on regulatory listings.. Assessed from 9 sources.

## Safety assessment

- Chemical concern score: 25/100 — Minor concern based on regulatory listings.
- Confidence: 4
- Rationale: Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).

## Regulatory status

- EU: allowed_listed — Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Product types: Rinse-off Maximum concentration: 0.0015% (of a mixture in the ratio 3:1 of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one
- EU: allowed_listed — Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0,0015 % Rinse-off products
- US: commercial use observed — EPA CPDat observed this chemical in 9337 composition records across product categories including Construction and building materials, Laboratory supplies, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Antioxidant, Processing aids not otherwise specified.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 1 drug products and 1 package presentations.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._