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Diisooctyl phthalate

CAS 27554-26-3 · 100/100 · High conf.

Also registered as 4 other CAS numbers

131-20-4 · 1330-91-2 · 25103-50-8 · 41375-90-0

Diisooctyl phthalate chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Diisooctyl phthalate in plain language

What it is

Also known as Isooctyl phthalate · 1,2-BENZENEDICARBOXYLIC acid, 1,2-DIISOOCTYL ester · Diisooctyl o-phthalate · Diisooctyl ester phthalic acid · bis(6-methylheptyl) benzene-1,2-dicarboxylate · 1,2-Benzenedicarboxylic acid, diisooctyl ester

Show all 23 names

Corflex 880 · Di-iso-octyl phthalate · Diisooctyl 1,2-benzenedicarboxylate · Diisooctyl phthalate (Clearance pending) · Diisooctylphthalate · Diop · Flexol Plasticizer DIOP · Hexaplas diop · Hexaplas M/O · Jayflex diop · Phthalic acid, bis(6-methylheptyl)ester · Unem 5005 · di-isooctyl phthalate · diisooctyl 1,2- benzendicarboxyl acid · diisooctyl 1,2- benzene dicarboxyl acid · diisooctyl 1,2-benzene dicarboxylacid · diisooctyl phthalate (diop)

What it does

Used in consumer products as a fragrance ingredient.

  • Fragrance
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Diisooctyl phthalate is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1667.
    • Cosmetics Regulation annex II / ref 1667.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 13 composition records across product categories including Raw materials, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Plasticizer, Fragrance.
    • EPA CPDat observed this chemical in 13 composition records across product categories including Raw materials, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Plasticizer, Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Diisooctyl phthalate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Diisooctyl phthalate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2021-11-03

    Open →
  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Diisooctyl phthalate in a product composition. These are source records, not Greenveil catalog products.

Source records

13

Named organisations

6

Raw materialsConstruction and building materials

Typical roles

Fragrance
See products using Diisooctyl phthalate →