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Amphetamine

CAS 300-62-9 · 100/100 · High conf.

Also registered as 3 other CAS numbers

60-15-1 · 17108-96-2 · 96332-84-2

Amphetamine chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Amphetamine in plain language

What it is

On cosmetic ingredient lists it appears as “N-adamantanoyl tyramine”.

Also known as N-adamantanoyl tyramine · N-cyclohexanoyl tyramine · N-nicotinoyl dopamine · N-nicotinoyl tyramine · Octopamine · Amfetamine

Show all 45 names

(±)-desoxynorephedrine · 1-Phenylpropan-2-amine · Amphetamine, dl- · Norephedrane · (+/-)-.alpha.-methylphenethylamine · (+/-)-1-Phenyl-2-aminopropane · (+/-)-Desoxynorephedrine · (+/-)-Phenylisopropylamine · (+/-)-α-Methylphenethylamine · (+/-)-α-Methylphenylethylamine · (+/-)-β-Phenylisopropylamine · (±)-.alpha.-methylphenethylamine · .beta.-aminopropylbenzene · 1-PHENYL-2-AMINOPROPANE · Adzenys er · Adzenys xr-odt · Amfetamin · Actedron · Allodene · Anorexide · Anorexine · Benzeneethanamine, .alpha.-methyl-, (+/-)- · Benzeneethanamine, .alpha.-methyl-, (±)- · Benzeneethanamine, .alpha.-methyl- · Benzeneethanamine, α-methyl- · DEA no. 1100 · Dyanavel · Desoxynorephedrine · Elastonon · Fenopromin · Mydayis (mixed salts of a single entity) · Phenedrine · Propisamine · Psychedrine · Raphetamine · Rhinalator · Simpatedrin · Sympatedrine · dl-Amphetamine

What it does

We don't have a plain-language description for Amphetamine yet.

Recorded functional uses: Pharmaceutical

Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • In marketed US drugs
  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 21.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 3 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.
    • EPA CPDat observed this chemical in 3 composition records across product categories including Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 23 active drug products and 23 total products.
    • FDA NDC lists this ingredient in 23 active drug products and 23 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Amphetamine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Amphetamine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2011-03-09

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (10)
Openfda substance

deadiversion.usdoj.gov

Openfda substance

deadiversion.usdoj.gov

Openfda substance

accessdata.fda.gov

Openfda substance

accessdata.fda.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

accessdata.fda.gov

Openfda substance

dailymed.nlm.nih.gov

Openfda substance

fco.factsandcomparisons.com

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

  • DairyContains · Oral (ingested)

    Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Amphetamine in a product composition. These are source records, not Greenveil catalog products.

Source records

23

Typical roles

Pharmaceutical
See products using Amphetamine →