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2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride

CAS 129829-22-7 · 100/100 · High conf.

Also registered as 1 other CAS number

3033-77-0

2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride in plain language

What it is

On cosmetic ingredient lists it appears as “2,3-EPOXYPROPYLTRIMONIIUM chloride”.

Also known as 2,3-EPOXYPROPYLTRIMONIIUM chloride · 3-EPOXYPROPYLTRIMONIIUM chloride · Glycidyltrimethylammonium chloride · Glycidyl trimethylammonium chloride · 2,3-EPOXYPROPYLTRIMONIUM chloride · N,N,N-Trimethyl(oxiran-2-yl)methanaminium chloride

Show all 25 names

trimethyl(oxiran-2-ylmethyl)azanium chloride · (.beta.,.gamma.-epoxypropyl)trimethylammonium chloride · (2,3-Epoxypropyl)trimethylammonium chloride · 1,2-EPOXY-3-(TRIMETHYLAMMONIO)PROPYL chloride · 1-(TRIMETHYLAMMONIO)-2,3-EPOXYPROPANE chloride · 2,3-EPOXYPROPYLTRIMETHYLAMMONIUM chloride · 2,3-epoxytrimethylammonium chloride · 2-Oxiranemethanaminium, N,N,N-trimethyl-, chloride (1:1) · Ammonium, (2,3-EPOXYPROPYL)TRIMETHYL-, chloride · Eptmac · G-mac · Glycidyl-trimethyl-ammonium chloride · Glytac A 100 · N,N,N-Trimethyloxiranemethanaminium chloride · N-Glycidyl-N,N,N-trimethylammonium chloride · Oxiranemethanaminium, n,n,n-trimethyl-, chloride · Oxiranemethanaminium, N,N,N-trimethyl-, chloride0 · Trimethylglycidylammonium chloride · gamma-Epoxypropyltrimethylammonium chloride beta

What it does

We don't have a plain-language description for 2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride yet.

Recorded functional uses: Not reported · No specific technical function

Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1B(),Mutagenic Cat. 2(),Reprotoxic Cat. 2()

    banned
    View source →
  • EUCosIngActive2 entries
    • 2,3-Epoxypropyltrimoniium Chloride is the quaternary ammonium salt that conforms to the formula: Restriction: II/1473Source →
    • Cosmetics Regulation annex II / ref 1473.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including No specific technical function.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including No specific technical function.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2020-07-30

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride in a product composition. These are source records, not Greenveil catalog products.

Named organisations

2

Typical roles

Not reportedNo specific technical function
See products using 2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride →