# 5,6-Dihydroxyindole

URL: https://app.greenveil.ai/ingredients/ingredient_cas_3131_52_0
Categories: beauty, industrial
Functions: Dye
Identifier: 3131-52-0

> 5,6-Dihydroxyindole is used as dye. Greenveil chemical-concern score: 70/100 — High concern based on regulatory listings.. Assessed from 6 sources.

## Safety assessment

- Chemical concern score: 70/100 — High concern based on regulatory listings.
- Confidence: 4
- Rationale: 1H-Indole-5,6-diol is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: restricted — Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Hair dye substance in oxidative hair dye products Other conditions: (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5% Conditions of use and warnings: To be printed on the label: Hair colorants can cause severe allergic reactions.
- US: commercial use observed — EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._