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2-Buten-1-one, 1-(2,4,4-trimethyl-2-cyclohexen-1-yl)-

CAS 33673-71-1 · 70/100 · High conf.

Concern score

70/100High concern based on regulatory listings.
High confidence

2-Buten-1-one, 1-(2,4,4-trimethyl-2-cyclohexen-1-yl)- in plain language

What it is

On cosmetic ingredient lists it appears as “Rose KETONE-5”.

Also known as Rose KETONE-5 · 1-(2,4,4-Trimethylcyclohex-2-en-1-yl)but-2-en-1-one · 1-(2,4,4-Trimethyl-2-cyclohexen-1-yl)-2-buten-1-one · 1-(2,4,4-Trimethyl-2-cyclohexenyl)-2-buten-1-one · Isodamascone · Ketone, propenyl 2,4,4-trimethyl-2-cyclohexen-1-yl

What it does

Used in cosmetics as a fragrance ingredient.

  • Perfuming
  • Fragrance
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

Rose ketone-5 (see note 16) 1-(2,4,4-Trimethyl-2-cycloehexen-1-yl)-2-buten-1-one is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Maximum concentration: 0.02%

    restricted
    View source →
  • EUCosIngActive2 entries
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Fragrance.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Fragrance.Source →

Expert safety opinions

No expert opinion on file for 2-Buten-1-one, 1-(2,4,4-trimethyl-2-cyclohexen-1-yl)-. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 2-Buten-1-one, 1-(2,4,4-trimethyl-2-cyclohexen-1-yl)- yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2013-05-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-03-19

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed 2-Buten-1-one, 1-(2,4,4-trimethyl-2-cyclohexen-1-yl)- in a product composition. These are source records, not Greenveil catalog products.

Named organisations

2

Typical roles

PerfumingFragrance
See products using 2-Buten-1-one, 1-(2,4,4-trimethyl-2-cyclohexen-1-yl)- →