Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- food
- pharma
Minoxidil
CAS 38304-91-5 · 100/100 · High conf.
Also registered as 1 other CAS number
16317-69-4
Concern score
100/100Critical concern based on regulatory listings.
High confidence
Minoxidil in plain language
On cosmetic ingredient lists it appears as “Minoxidil hyaluronamide”.
Also known as Minoxidil hyaluronamide · Minoxidil oxothiazolidinecarboxylate · Minoxidil succinoyl DECAPEPTIDE-18 · Minoxidil succinoyl OLIGOPEPTIDE-143 · 2,4-DIAMINO-6-PIPERIDINOPYRIMIDINE 3-OXIDE. · 3-Oxo-6-(piperidin-1-yl)-3lambda~5~-pyrimidine-2,4-diamine
Show all 29 names
2,4-Diamino-6-piperidinopyrimidine 3-N-oxide · 2,4-Diamino-6-piperidinopyrimidine 3-oxide · 2,4-Pyrimidinediamine, 6-(1-Piperidinyl)-, 3-Oxide · 2,6-Diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate · 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine · 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperodinopyrimidine · Alopexil · Alostil · Loniten · Lonolox · Minodyl · Minoximen · Mintop · Normoxidil · Pierminox · Prexidil · Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide · Riup · Rogaine · Theroxidil · Tricoxidil · U-10,858 · U-10858
Used in cosmetics as a hair conditioner and a hair fixative. Minoxidil is the heterocyclic compound.
- Hair conditioning
- Hair fixing
- Conditioner
- Hair fixative
- Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
Why it's flagged
6-(Piperidinyl)-2,4-pyrimidinediamine-3-oxide (Minoxidil (INN)) and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- In marketed US drugs
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Beauty
- Pharma
- Food
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
USEPAcommercial use observedEPA CPDat observed this chemical in 5 composition records across product categories including Food and drug, Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Hair fixative.
- EPA CPDat observed this chemical in 5 composition records across product categories including Food and drug, Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Hair fixative.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 296 active drug products and 311 total products.
- FDA NDC lists this ingredient in 296 active drug products and 311 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Minoxidil. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Minoxidil yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2024-11-22
- Open →
EPA Chemical and Products Database
exposure · updated July 2016
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2031-03-07
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often FDA National Drug Code directory has listed Minoxidil in a product composition. These are source records, not Greenveil catalog products.
Source records
311
Typical roles
Hair conditioningHair fixingConditionerHair fixative
Found in these products
Cosmetic and personal-care products that list Minoxidil are shown first. Their ingredient lists include Minoxidil; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
