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Phenprocoumon

CAS 435-97-2 · 100/100 · High conf.

Also registered as 2 other CAS numbers

70206-44-9 · 5999-41-7

Phenprocoumon chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Phenprocoumon in plain language

What it is

Also known as Phenprocoumon (INN) · (±)-phenprocoumon · 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one · 4-hydroxy-3-(1-phenylpropyl)chromen-2-one · DL-3-(.ALPHA.-ETHYLBENZYL)-4-HYDROXYCOUMARIN · Fencumar

Show all 32 names

Marcoumar · Marcumar · Phenprocoumarol · Phenprocoumarole · (.+-.)-Phenprocoumon · 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-phenylpropyl)- · 3-(.ALPHA.-ETHYLBENZYL)-4-HYDROXYCOUMARIN · 3-(.ALPHA.-PHENYLPROPYL)-4-HYDROXYCOUMARIN · 3-(1'-Phenyl-propyl)-4-oxycoumarin · 3-(1-Phenylpropyl)-4-hydroxycoumarin · 3-(α-Ethylbenzyl)-4-hydroxycoumarin · 3-(α-Phenylpropyl)-4-hydroxycoumarin · 4-Hydroxy-2-oxo-3-(1-phenylpropyl)-2H-chromene · 4-Hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one · BS-7565 · Coumarin, 3-(.ALPHA.-ETHYLBENZYL)-4-HYDROXY- · Coumarin, 3-(α-ethylbenzyl)-4-hydroxy- · DL-3-(α-Ethylbenzyl)-4-hydroxycoumarin · Falithrom · Fenprocumone · Liquamar · Phenprocoumone · Phenprocoumonum · Phenprocumone · RO-1-4849 · fenprocumon

What it does

We don't have a plain-language description for Phenprocoumon yet.

Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Phenprocoumon (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 273.
    • Cosmetics Regulation annex II / ref 273.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Phenprocoumon. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Phenprocoumon yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-15

    Open →
  • EPA Chemical and Products Database

    exposure · updated March 8, 2019

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Phenprocoumon in a product composition. These are source records, not Greenveil catalog products.

Named organisations

5

See products using Phenprocoumon →