- beauty
- cleaning
Genistein
CAS 690224-00-1 · 70/100 · High conf.
Also registered as 2 other CAS numbers
944110-99-0 · 446-72-0
Concern score
70/100High concern based on regulatory listings.
High confidence
Genistein in plain language
Also known as 4',5,7-TRIHYDROXYISOFLAVONE · 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one · 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one · Sophoricol · 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)- · 5,7,4'-Trihydroxyisoflavone
Show all 24 names
5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-CHROMEN-4-ONE · 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyron · 5,7-dihidroxi-3-(4-hidroxifenil)-4-benzopirona · 5,7-dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone · 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one · BIO-300 · Baichanin A · Bonistein · FW-635I-2 · Genestein · Genisteol · Genisterin · Isoflavone, 4',5,7-trihydroxy- · NPI-031L · Prunetol · SIPI-807-1 · Genistein (constituent of red clover) · Genistein (constituent of soy isoflavones)
Used in cosmetics as a skin-conditioning agent.
- Skin conditioning
- Conditioner
- High concern: no hazard classifications on record. It is restricted in EU cosmetics.
Why it's flagged
Genisteol; 4',5,7-Trihydroxyisoflavone; 5,7-dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — restricted
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- EU Annex III — restricted
- EU restricted in cosmetics
- Found in consumer products
- Beauty
- Cleaning
- View source →restricted
EUEC
Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Maximum concentration: 0,007 % Other conditions: From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.
USEPAcommercial use observedEPA CPDat observed this chemical in 32 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
- EPA CPDat observed this chemical in 32 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Genistein. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Genistein yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2024-04-04
- Open →
EPA Chemical and Products Database
exposure · updated September 2013
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed Genistein in a product composition. These are source records, not Greenveil catalog products.
Source records
32
Named organisations
6
Personal care
Typical roles
Skin conditioningConditioner
Found in these products
Cosmetic and personal-care products that list Genistein are shown first. Their ingredient lists include Genistein; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
