Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
- beauty
- industrial
Bismarck Brown R Base
CAS 4482-25-1 · 100/100 · High conf.
Also registered as 1 other CAS number
1071756-64-3
Concern score
100/100Critical concern based on regulatory listings.
High confidence
Bismarck Brown R Base in plain language
On cosmetic ingredient lists it appears as “Basic brown 4”.
Also known as Basic brown 4 · Bismark brown r free base · Solvent brown 12 · Basic brown 4 free base · Bismarck brown base ns · Bismarck brown g base
Show all 16 names
Bismarck brown rx base · Bismarck brown tss base · Bismarck brown x base · Brasilazina brown r base · C.I. 21010:1 · C.I. solvent brown 12 · MLS000736629 · SMR000528226 · UNII-357RPV4TE1 · solvent brown
Used in cosmetics as a hair dye.
- Hair dyeing
- Colourant
- Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
Why it's flagged
4,4'-[(4-Methyl-1,3-phenylene)bis(azo)]bis[6-methyl-1,3-benzenediamine] (Basic Brown 4) and its salts, when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Bismarck Brown R Base. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Bismarck Brown R Base yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2010-10-21
- Open →
EPA Chemical and Products Database
exposure · updated 2020-02-13
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Where it has been recorded
How often EPA CPDat has listed Bismarck Brown R Base in a product composition. These are source records, not Greenveil catalog products.
Named organisations
1
Typical roles
Hair dyeingColourant