# rel-(1R,4S,4aS,5R,8S,8aR)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene

URL: https://app.greenveil.ai/ingredients/ingredient_cas_465_73_6
Categories: beauty, industrial
Identifier: 465-73-6

> rel-(1R,4S,4aS,5R,8S,8aR)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Assessed from 6 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence: 4
- Rationale: (1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene (Isodrin-ISO) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
- US: commercial use observed — EPA CPDat observed this chemical in 2 composition records across product categories including Laboratory supplies.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._