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Basic red 2

CAS 74109-45-8 · 100/100 · High conf.

Also registered as 1 other CAS number

477-73-6

Basic red 2 chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Basic red 2 in plain language

What it is

Also known as C.I. basic red 2 · 3,7-Diamino-2,8-dimethyl-5-phenylphenazin-5-ium chloride · 3,7-dimethyl-10-phenylphenazin-10-ium-2,8-diamine chloride · C.I. 50240 · CI 50240 · Safranin

Show all 28 names

Safranine o · Safranine t · 3,7-Diamino-2,8-dimethyl-5-phenyl-phenazinium, Chloride · 3,7-Diamino-2,8-dimethyl-5-phenylphenazinium chloride · Gossypimine · Safranin T · Safranine · Safranine A · Safranine B · Safranine G · Safranine GF · Safranine J · Safranine OK · Safranine TH · Safranine TN · Safranine TS · Safranine Y · Safranine YN · Safranine Zh · Tolusafranine · safranin o · safranin o (einecs/elincs: 207-518-8)

What it does

Used in cosmetics as a hair dye.

  • Hair dyeing
  • Colourant
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl- and its salts, when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Pharma
  • Food
  • Industrial

  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActive2 entries
  • USEPAcommercial use observedEPA CPDat observed this chemical in 39 composition records across product categories including Laboratory supplies, Food and drug. EPA CPDat classifies this chemical for functional uses including Dye.
    • EPA CPDat observed this chemical in 39 composition records across product categories including Laboratory supplies, Food and drug. EPA CPDat classifies this chemical for functional uses including Dye.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Basic red 2. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Basic red 2 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-21

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Basic red 2 in a product composition. These are source records, not Greenveil catalog products.

Source records

39

Named organisations

2

Laboratory suppliesFood and drug

Typical roles

Hair dyeingColourant
See products using Basic red 2 →