Cyclophosphamide

Cyclophosphamide in plain language

What it is

Also known as Cyclophosphamide anhydrous · Cyclophosphamide (INN) and its salts · Anhydrous cyclophosphamide · Cyclophosphamide lyophilized · (.+-.)-Cyclophosphamide · (RS)-Cyclophosphamide

Show all 31 names

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester · Clafen · Claphene · Cyclophosphamid · Cyclophosphamide (anhydrous) · Cyclophosphamide (hydrated) · Cyclophosphamidum · Cyclophosphan · Cyclophosphane · Cyclophosphoramide · Cyclostin · Cytophosphan · Cytophosphane · Cytoxan · Endoxan · Endoxan R · Endoxana · Endoxanal · Genoxal · Mitoxan · Procytox · Sendoxan · Zyklophosphamid · ciclofosfamida · cyclophosphamide (sara iii)

What it does

We don't have a plain-language description for Cyclophosphamide yet.

Is it a concern?

Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Cyclophosphamide (INN) and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• In marketed US drugs
• EU Annex II — prohibited
• EU prohibited in cosmetics

• EU·EC

  Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

  banned
  View source →

• EU·CosIng·ActiveCosmetics Regulation annex II / ref 88.

  • Cosmetics Regulation annex II / ref 88.Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 8 composition records across product categories including Laboratory supplies.

  • EPA CPDat observed this chemical in 8 composition records across product categories including Laboratory supplies.Source →
• US·FDA·marketed drug occurrenceFDA NDC lists this ingredient in 5 active drug products and 5 total products.

  • FDA NDC lists this ingredient in 5 active drug products and 5 total products.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Cyclophosphamide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.