Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
(-)-Epinephrine
Epinephrine (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
Research docs0Claims0Sources7FunctionPharmaceuticalIdentifier51-43-4
Concern score
100/100Critical concern based on regulatory listings.
Well researched
How we scored this
The concern value reflects this ingredient's chemical identity — its hazard profile from the published classifications and regulatory status below — not the safety of a product it appears in. A score near 40 is the baseline for ingredients with no specific signal (water scores 40 by design), so a mid-range value is not a safety verdict.
Concern score 100/100 (critical) · high confidence.
Regional restrictions
- EU — banned · Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
Where it appears
Prevalence of (-)-Epinephrine in our catalog (fda_ndc).
Products
264
Typical roles
Pharmaceutical
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
Allergen profile
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
- SulphitesContains · Oral (ingested)
Source: chemindex_name_match
Linked research
Primary documents currently linked to this ingredient record.
No linked research documents are attached to this ingredient yet.
Extracted claims
Structured claim signals pulled from linked ingredient research.
No extracted claims are attached to this ingredient yet.
Regulatory status
Published jurisdiction-level classifications and regulatory designations for this ingredient.
EU
EC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
Effective: 2010-10-15View source →
US
EPA
EPA CPDat observed this chemical in 52 composition records across product categories including Food and drug, Medical/dental, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.
Effective: 2020-08-31View source →
US
FDA