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Atropine, its salts and derivatives

CAS 51-55-8 · 100/100 · High conf.

Also registered as 2 other CAS numbers

78597-12-3 · 1445960-43-9

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Atropine, its salts and derivatives in plain language

What it is

Also known as Atropine · (+/-)-Atropine · (3-ENDO)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL tropate · (±)-hyoscyamine · 1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (±)-tropate (ester) · Atropine ((±)-)

Show all 18 names

Dl-hyoscyamine · (+/-)-Hyoscyamine · 1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (+/-)-tropate (ester) · 1αH,5αH-Tropan-3α-ol · Atropen · Atropine ((+/-)) · Atropin · atropina · atropine free base crystalline · Atnaa component atropine · Atropinum · Duodote component atropine

What it does

We don't have a plain-language description for Atropine, its salts and derivatives yet.

Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Atropine, its salts and derivatives is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 45.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including unclassified products.
    • EPA CPDat observed this chemical in 2 composition records across product categories including unclassified products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Atropine, its salts and derivatives. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Atropine, its salts and derivatives yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-15

    Open →
  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (6)
Openfda substance

fco.factsandcomparisons.com

Openfda substance

eurofinsdiscovery.com

Openfda substance

eurofinsdiscovery.com

Openfda substance

eurofinsdiscovery.com

Openfda substance

accessdata.fda.gov

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Atropine, its salts and derivatives in a product composition. These are source records, not Greenveil catalog products.

Source records

2

Named organisations

6

See products using Atropine, its salts and derivatives →