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N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN)

CAS 541-20-8 · 100/100 · High conf.

N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) in plain language

What it is

Also known as Pentamethonium bromide · Pentamethylenebis · Pentametonio bromuro · Pentamethonium dibromide · Pentamethylenebis(trimethylammonium bromide) · 1,5-Pentanediaminium, N,N,N,N′,N′,N′-hexamethyl-, dibromide

Show all 17 names

Bromure de pentamethonium · Bromuro de pentametonio · C 5 · C 5 (van) · Lytensium · N1,N1,N1,N5,N5,N5-hexamethylpentane-1,5-diaminium bromide · Pentamethonii bromidum · Penthonium · alpha,omega-Bis(trimethylammonium)pentane dibromide · pentamAthonium (cation) · α,ω-Bis(trimethylammonium)pentane dibromide

What it does

We don't have a plain-language description for N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) yet.

Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 120.
    • Cosmetics Regulation annex II / ref 120.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN). These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-20

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) in a product composition. These are source records, not Greenveil catalog products.

Named organisations

2

See products using N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) →

Catalog

Found in these products

Their ingredient lists include N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN); each product's own rating depends on its whole formula, so it is shown on the product page, not here.