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Tetramethyl acetyloctahydronaphthalenes

CAS 54464-57-2 · 70/100 · High conf.

Also registered as 3 other CAS numbers

54464-59-4 · 68155-66-8 · 68155-67-9

Concern score

70/100High concern based on regulatory listings.
High confidence

Tetramethyl acetyloctahydronaphthalenes in plain language

What it is

Also known as (1-(OCTAHYDRO-TETRAMETHYL-2-NAPHTHALENYL)-ETHAN-1-ONE · Anthamber · Iso velvetone · Orbitone · Patchouli ethanone · Otne

Show all 7 names

iso e super

What it does

Used in cosmetics as a skin-conditioning agent and a fragrance ingredient. Tetramethyl Acetyloctahydronaphthalenes is a mixture of isomers.

  • Skin conditioning
  • Perfuming
  • Fragrance
  • Conditioner
  • Deodorant
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl- 2-naphthyl)ethan- 1-one; 1-(1,2,3,4,5,6,7,8-octahydro-2,3,5,5-tetramethyl- 2-naphthyl)ethan- 1-one; 1-(1,2,3,5,6,7,8,8a- octahydro-2,3,8,8-tetramethyl- 2-naphthyl)ethan- 1-one; 1-(1,2,3,4,6,7,8,8a- octahydro-2,3,8,8-tetramethyl- 2-naphthyl)ethan- 1-one is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial

  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Other conditions: The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

    restricted
    View source →
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex III / ref 344.Source →
    • Tetramethyl Acetyloctahydronaphthalenes is a mixture of isomers that conforms to the following formulae: Restriction: III/344Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 276 composition records across product categories including Personal care, Cleaning products and household care, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Fragrance, Deodorizer, Softener and conditioner.
    • EPA CPDat observed this chemical in 276 composition records across product categories including Personal care, Cleaning products and household care, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Fragrance, Deodorizer, Softener and conditioner.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as mixture.
    • openFDA substance registry classifies this ingredient as mixture.Source →

Expert safety opinions

No expert opinion on file for Tetramethyl acetyloctahydronaphthalenes. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Tetramethyl acetyloctahydronaphthalenes yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2023-10-03

    Open →

  • EPA Chemical and Products Database

    exposure · updated November 2014

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (2)
Openfda substance

thegoodscentscompany.com

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Tetramethyl acetyloctahydronaphthalenes in a product composition. These are source records, not Greenveil catalog products.

Source records

276

Named organisations

6

Personal careCleaning products and household careCleaning and safetyVehiclePesticides

Typical roles

Skin conditioningPerfumingFragranceConditionerDeodorant
See products using Tetramethyl acetyloctahydronaphthalenes →

Catalog

Found in these products

Their ingredient lists include Tetramethyl acetyloctahydronaphthalenes; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 322 →Find products without it →