- beauty
- food
- industrial
- pharma
Isoniazid
CAS 54-85-3 · 100/100 · High conf.
Also registered as 4 other CAS numbers
7640-37-1 · 37271-10-6 · 41466-07-3 · 62229-51-0
Concern score
Isoniazid in plain language
On cosmetic ingredient lists it appears as “Adipic acid dihydrazide”.
Also known as Adipic acid dihydrazide · Stearic hydrazide · Isonicotinic acid hydrazide · 4-PYRIDINECARBOXYLIC acid hydrazide · Hydrazides and their salts e.g. Isoniazid (INN) · 4-PYRIDINECARBOXYLIC acid, hydrazide
Show all 46 names
Armazid · Armazide · Atcotibine · Cedin · Cotinazin · Dianicotyl · Dinacrin · Ditubin · Eralon · Ertuban · Hidrasonil · Hydrazid · Ipcazide · Isidrina · Isobicina · Isonicotan · Mybasan · Neumandin · Pyridine-4-carbohydrazide · Teebaconin · Tisiodrazida · 4-(Hydrazinocarbonyl)pyridine · 4-Pyridinecarbonylhydrazine · 4-Pyridinecarboxylic acid hydrazine · 4-Pyridinecarboxylic hydrazide · 4-Pyridylcarbonylhydrazide · Dow-isoniazid · Hyzyd · Inh · Iscotin · Isonicotinylhydrazine · Isoniazide · Isonicotinohydrazide · Laniazid · Nydrazid · Rimifon · Stanozide · hydrazide · Rifamate component isoniazid · Rifater component isoniazid
We don't have a plain-language description for Isoniazid yet.
- Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
Why it's flagged
Hydrazides and their salts e.g. Isoniazid (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- In marketed US drugs
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Pharma
- Food
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
EUCosIngActiveCosmetics Regulation annex II / ref 200.
- Cosmetics Regulation annex II / ref 200.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Food and drug, Laboratory supplies.
- EPA CPDat observed this chemical in 4 composition records across product categories including Food and drug, Laboratory supplies.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 16 active drug products and 29 total products.
- FDA NDC lists this ingredient in 16 active drug products and 29 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Isoniazid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
JECFA
Joint FAO/WHO Expert Committee on Food Additives
No JECFA evaluation on file.
EFSA
European Food Safety Authority
No EFSA opinion on file.
Evidence & sources
No graded research studies for Isoniazid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2010-10-20
- Open →
EPA Chemical and Products Database
exposure · updated 2020-08-31
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA National Drug Code Directory
regulatory · updated 2028-02-28
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often FDA National Drug Code directory has listed Isoniazid in a product composition. These are source records, not Greenveil catalog products.
Source records
29