# CHLORHEXIDINE

URL: https://app.greenveil.ai/ingredients/ingredient_cas_55_56_1
Categories: beauty, pharma
Functions: preservative, Biocide, Oral Care Agent, Preservative, oral care
Identifier: 55-56-1

> CHLORHEXIDINE is used as preservative / biocide. Greenveil chemical-concern score: 25/100 — Minor concern based on regulatory listings.. Assessed from 8 sources.

## Safety assessment

- Chemical concern score: 25/100 — Minor concern based on regulatory listings.
- Confidence: 4
- Rationale: N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).

## Regulatory status

- EU: allowed_listed — Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.3% (as chlorhexidine)
- US: commercial use observed — EPA CPDat observed this chemical in 30 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Biocide, Preservative, oral care.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 4 active drug products and 4 total products.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 3 active drug products and 3 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._