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4-Methoxytoluene-2,5-diamine dihydrochloride

CAS 56496-88-9 · 100/100 · High conf.

4-Methoxytoluene-2,5-diamine dihydrochloride chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

4-Methoxytoluene-2,5-diamine dihydrochloride in plain language

What it is

On cosmetic ingredient lists it appears as “4-METHOXYTOLUENE-2”.

Also known as 4-METHOXYTOLUENE-2 · 4-METHOXYTOLUENE-2,5-DIAMINE hcl · 5-DIAMINE HCl · 1,4-BENZENEDIAMINE, 2-METHOXY-5-METHYL-, dihydrochloride · 2-METHOXY-5-METHYL-P-PHENYLENEDIAMINE dihydrochloride · 2-METHYL-5-METHOXY-P-PHENYLENEDIAMINE dihydrochloride

Show all 17 names

2-methoxy-5-methylbenzene-1,4-diamine;dihydrochloride · 1,4-Benzenediamine, 2-methoxy-5-methyl-, hydrochloride (1:2) · 2-METHOXY-5-METHYL-1,4-PHENYLENEDIAMINE hydrochloride · 2-Methoxy-5-methylbenzene-1,4-diamine dihydrochloride · 2-methoxy-5-methyl paraphenylenediamine dihydrochloride · 2-methyl-5-methoxy paraphenylene diamine dihydrochloride · 4-Methoxytoluene-2,5-Diamine hydrochloride · Mauayddabcdbrg-uhfffaoysa-n · Q27293730 · UNII-X9JJM46RYT · starbld0006670

What it does

Used in cosmetics as a hair dye.

  • Hair dyeing
  • Colourant
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

4-Methoxytoluene-2,5-diamine and its HCl salt, when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActive2 entries
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 4-Methoxytoluene-2,5-diamine dihydrochloride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 4-Methoxytoluene-2,5-diamine dihydrochloride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-15

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 4-Methoxytoluene-2,5-diamine dihydrochloride in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

Hair dyeingColourant
See products using 4-Methoxytoluene-2,5-diamine dihydrochloride →