Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Toluene 2,4-diisocyanate
4-Methyl-m-phenylene diisocyanate (Toluene 2,4-diisocyanate) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
Research docs0Claims0Sources6Functioncrosslinking / coupling / curing agents > diisocyanates • Processing aids not otherwise specifiedIdentifier584-84-9
Concern score
100/100Critical concern driven by cmr.
Well researched
How we scored this
The concern value reflects this ingredient's chemical identity — its hazard profile from the published classifications and regulatory status below — not the safety of a product it appears in. A score near 40 is the baseline for ingredients with no specific signal (water scores 40 by design), so a mid-range value is not a safety verdict.
Concern score 100/100 (critical) · high confidence.
Regional restrictions
- EU — banned · Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()
Where it appears
Prevalence of Toluene 2,4-diisocyanate in our catalog (epa_cpdat).
Products
379
Brands
6
VehicleRaw materialsIndustrial productsHome maintenanceConstructionSpecialty occupational products
Typical roles
crosslinking / coupling / curing agents > diisocyanatesProcessing aids not otherwise specifiedSolvent
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Evidence read
The published evidence profile currently shaping this ingredient record.
No evidence profiles are attached to this ingredient yet.
Allergen profile
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
- SoyContains · Oral (ingested)
Source: chemindex_name_match
Linked research
Primary documents currently linked to this ingredient record.
No linked research documents are attached to this ingredient yet.
Extracted claims
Structured claim signals pulled from linked ingredient research.
No extracted claims are attached to this ingredient yet.
Regulatory status
Published jurisdiction-level classifications and regulatory designations for this ingredient.
EU
EC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 2()
Effective: 2019-07-03View source →
US
EPA
EPA CPDat observed this chemical in 379 composition records across product categories including Vehicle, Raw materials, Industrial products. EPA CPDat classifies this chemical for functional uses including Solvent, Processing aids not otherwise specified, crosslinking / coupling / curing agents > diisocyanates.
Effective: February 2019View source →
US
FDA