Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
- beauty
- industrial
- pharma
Pyrilamine maleate
CAS 59-33-6 · 100/100 · High conf.
Concern score
100/100Critical concern based on regulatory listings.
Well researched
Why it's flagged
2-[4-Methoxybenzyl-N-(2-pyridyl)amino]ethyldimethylamine maleate (Mepyramine maleate; pyrilamine maleate) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- commercial_presence
- cpdat_category:industrial
- currently_marketed_ndc
- definition_level:complete
- definition_type:primary
- eu_annex:II
- eu_cosmetic_banned
- ingredient_type:ingredient substance
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 83 active drug products and 90 total products.
- FDA NDC lists this ingredient in 83 active drug products and 90 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Evidence
No graded sources yet for Pyrilamine maleate. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Where it appears
Prevalence of Pyrilamine maleate in our catalog (fda_ndc).
Products
90
