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N,N'-Diacetylbenzidine

CAS 613-35-4 · 100/100 · High conf.

N,N'-Diacetylbenzidine chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

N,N'-Diacetylbenzidine in plain language

What it is

Also known as 4,4'-DIACETYLBENZIDINE · 4',4'''-BIACETANILIDE · N,N'-4,4'-BIPHENYLYLENEBISACETAMIDE · 4,4'-DIACETAMIDOBIPHENYL · 4,4'-DIACETYLAMINOBIPHENYL · Acetamide, N,N'-4,4'-biphenylylenebis-

Show all 14 names

Benzidine, N,N'-diacetyl- · Biphenyl, 4,4'-diacetamido- · Diacetylbenzidine, n,n- · Diacetylbenzidine · N,N'-(1,1'-BIPHENYL)-4,4'-DIYLBISACETAMIDE · N,N'-(1,1'-Biphenyl)-4,4'-diylbis-acetamide · N,N'-Diacetyl benzidine · N,N-Diacetylbenzidine

What it does

We don't have a plain-language description for N,N'-Diacetylbenzidine yet.

Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

N,N'-Diacetylbenzidine is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial

  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1B(),Mutagenic Cat. 2()

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 1502.
    • Cosmetics Regulation annex II / ref 1502.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for N,N'-Diacetylbenzidine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for N,N'-Diacetylbenzidine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2020-07-30

    Open →

  • EPA Chemical and Products Database

    exposure · updated March 8, 2019

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed N,N'-Diacetylbenzidine in a product composition. These are source records, not Greenveil catalog products.

Named organisations

3

See products using N,N'-Diacetylbenzidine →