- beauty
- food
- industrial
- pharma
Methylene blue anhydrous
CAS 61-73-4 · 100/100 · High conf.
Also registered as 13 other CAS numbers
150645-86-6 · 152071-32-4 · 1341-90-8 · 6476-03-5 · 12262-49-6 · 97130-83-1 · 105504-42-5 · 121067-62-7 · 167498-52-4 · 923927-02-0 · 1001913-24-1 · 1001914-35-7 · 1219638-11-5
Dye
Concern score
100/100Critical concern based on regulatory listings.
High confidence
Why it's flagged
Phenothiazin-5-ium, 3,7-bis(dimethylamino)- and its salts, when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Beauty
- Pharma
- Food
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
USEPAcommercial use observedEPA CPDat observed this chemical in 48 composition records across product categories including Raw materials, Laboratory supplies, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including Dye.
- EPA CPDat observed this chemical in 48 composition records across product categories including Raw materials, Laboratory supplies, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including Dye.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Evidence & sources
No graded research studies for Methylene blue anhydrous yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2010-10-15
- Open →
EPA Chemical and Products Database
exposure · updated January 7, 2008
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (2)
ema.europa.eu
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed Methylene blue anhydrous in a product composition. These are source records, not Greenveil catalog products.
Source records
48
Named organisations
6
Raw materialsLaboratory suppliesSpecialty occupational productsPersonal careFood and drug
Typical roles
Dye
