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Nicotinyl alcohol hydrofluoride

CAS 62756-44-9 · 70/100 · High conf.

Nicotinyl alcohol hydrofluoride chemical structure

Concern score

70/100High concern based on regulatory listings.
High confidence

Nicotinyl alcohol hydrofluoride in plain language

What it is

On cosmetic ingredient lists it appears as “Nicomethanol hydrofluoride”.

Also known as Nicomethanol hydrofluoride · Nicotinyl alcohol hf · Nicomethanol fluorhydrate · pyridin-3-ylmethanol;hydrofluoride · (pyridin-3-yl)methanol hydrofluoride · 3-PYRIDINEMETHANOL hydrogen fluoride

Show all 16 names

3-Pyridinemethanol hydrofluoride · 3-Pyridinemethanol, hydrofluoride (1:1) · 3-pyridyl methanol hydrofluoride · AKOS028109945 · Ec 700-352-1 · Fluorinol · Fluoronicomethanol · Pp 117 · Q27264077 · UNII-67656KJH8M

What it does

Used in cosmetics as an antiplaque.

  • Antiplaque
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

Nicomethanol Hydrofluoride is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Oral products Maximum concentration: 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 % Conditions of use and warnings: Contains nicomethanol hydrofluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult use only") the following labelling is obligatory: "Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimise swallowing. In case of intake of…

    restricted
    View source →
  • EUCosIngActive2 entries
    • Nicotinyl Alcohol HF is the organic compound.Source →
    • Cosmetics Regulation annex III / ref 47.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Nicotinyl alcohol hydrofluoride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Nicotinyl alcohol hydrofluoride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2013-05-14

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-02-13

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Catalog

Found in these products

Cosmetic and personal-care products that list Nicotinyl alcohol hydrofluoride are shown first. Their ingredient lists include Nicotinyl alcohol hydrofluoride; each product's own rating depends on its whole formula, so it is shown on the product page, not here.