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Siloxanes and Silicones, di-Me

CAS 12648-49-6 · 20/100 · High conf.

Also registered as 11 other CAS numbers

167748-54-1 · 1471301-69-5 · 1669409-87-3 · 1669410-33-6 · 2028348-45-8 · 2161362-23-6 · 2356309-79-8 · 2409833-01-6 · 9006-65-9 · 9016-00-6 · 63148-62-9

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Siloxanes and Silicones, di-Me in plain language

What it is

On cosmetic ingredient lists it appears as “Dimethicone”.

Also known as Dimethicone · Dimethyl polysiloxane (E 900) · Polydimethylsiloxane · Anti-foam agent · By 222-067R · Trimethylsilyoxy-terminated dimethyl siloxane

Show all 20 names

Dehesive 940A · Dehesive 942 · Dicsilicone Softener 120 · Dicsilicone Softener 300 · Dimethyl silicones and siloxanes · di-Me Polysiloxanes · Silicone · Silicone polymer · dimeticone · dimeticonum · poly (dimethylsiloxane) · poly (dimethylsiloxane) (me term) · silicon fluid · silicon fluid/silicone grease

What it does

Used in cosmetics as an emollient, a skin-conditioning agent and a skin protectant.

  • Emollient
  • Skin conditioning
  • Skin protecting
  • Antifoaming
  • Surfactant
  • Fragrance
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 2 composition records across product categories including Cleaning products and household care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Siloxanes and Silicones, di-Me appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Industrial
  • USEPAcommercial use observed2 entries
    • EPA CPDat observed this chemical in 2 composition records across product categories including Cleaning products and household care.Source →
    • EPA CPDat observed this chemical in 1162 composition records across product categories including Construction and building materials, Home maintenance, Cons. electronics, mech. appliances, and machinery. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Defoamer, Binder.Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAEFSA opinionRe-evaluation of dimethyl polysiloxane (E 900) as a food additive (EFSA FAF)
    • Re-evaluation of dimethyl polysiloxane (E 900) as a food additive (EFSA FAF)Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Re-evaluation of dimethyl polysiloxane (E 900) as a food additive (EFSA FAF)

      2020 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Siloxanes and Silicones, di-Me yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-04-22

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Siloxanes and Silicones, di-Me in a product composition. These are source records, not Greenveil catalog products.

Source records

2

Named organisations

7

Cleaning products and household care

Typical roles

EmollientSkin conditioningSkin protectingAntifoamingSurfactantFragrance
See products using Siloxanes and Silicones, di-Me →

Catalog

Found in these products

Their ingredient lists include Siloxanes and Silicones, di-Me; each product's own rating depends on its whole formula, so it is shown on the product page, not here.