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  1. Ingredients
  2. beauty
  3. Colchicine
  • beauty
  • food
  • pharma

Colchicine

CAS 64-86-8 · 100/100 · High conf.

Colchicine chemical structure
100

Concern score

100/100Critical concern driven by cmr.
Well researched
Colchicine chemical structure

Why it's flagged

  • Cmr

Colchicine, its salts and derivatives is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • commercial_presence
  • consumer_product_presence
  • cpdat_category:pharma|food
  • currently_marketed_ndc
  • definition_level:complete
  • definition_type:primary
  • eu_annex:II
  • eu_cmr
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Mutagenic Cat. 1B()

    banned
    View source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including Food and drug.
    • EPA CPDat observed this chemical in 2 composition records across product categories including Food and drug.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 52 active drug products and 53 total products.
    • FDA NDC lists this ingredient in 52 active drug products and 53 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Evidence

No graded sources yet for Colchicine. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it appears

Prevalence of Colchicine in our catalog (fda_ndc).

Products

53

See products using Colchicine →